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Table 2 One-year follow-up of family-based treatment of 201 adolescents with restrictive eating disorders with features of anorexia nervosa but not fulfilling the weight criterion

From: Family-based intervention in adolescent restrictive eating disorders: early treatment response and low weight suppression is associated with favourable one-year outcome

  EDE-Q global score at 1-year follow-up Eating disorder at 1-year follow-up
<2.0 ≥2.0 No eating disorder Persisting eating disorder
n 130 71 106 95
Premorbid
 Age at top weight (years) 14.1 ± 1.7 14.2 ± 1.8 14.2 ± 1.6 14.0 ± 1.8
 BMISDS at top weight 0.55 ± 1.03 1.03 ± 0.88** 0.63 ± 0.93 0.76 ± 1.08
Presentation
 Gender (n; M/F) 12/118 1/71* 11/96 2/93*
 Age (years) 14.9 ± 1.6 15.2 ± 1.8 15.0 ± 1.6 15.0 ± 1.8
 Duration of ED symptoms (months) 9.5 ± 8.4 9.9 ± 9.3 10.6 ± 9.2 8.5 ± 8.0
 BMISDS −0.69 ± 1.10 −0.32 ± 0.88* −0.56 ± 1.08 −0.57 ± 0.99
 Weight loss (kg) 5.9 ± 5.2 7.2 ± 6.3 5.8 ± 5.4 6.9 ± 5.9
 Weight suppression (SDS) 1.25 ± 0.86 1.33 ± 0.87 1.20 ± 0.90 1.37 ± 0.81
 Exercise for weight control (n) 91 (70%) 48 (68%) 72 (68%) 67 (71%)
 Vomiting for weight control (n) 23 (18%) 16 (23%) 21 (20%) 18 (19%)
 Self-destructive behaviour (n) 15 (12%) 8 (11%) 11 (10%) 12 (13%)
 EDE-Q global score 2.6 ± 1.7 3.6 ± 1.6*** 2.6 ± 1.6 3.2 ± 1.7*
 MADRS-S 16 ± 10 22 ± 11*** 16 ± 10 20 ± 11*
 Depression (n) 23 (18%) 20 (28%) 18 (17%) 25 (26%)
 Neuropsychiatric diagnoses (n) 6 (5%) 3 (4%) 6 (5%) 3 (3%)
Start of treatment
 Parents accomplishing interventions during 1st week (n) 95/127 (75%) 41/65 (63%) 74/103 (72%) 62/89 (70%)
 1-week weight gain (kg) 0.6 ± 1.0 0.3 ± 0.8* 0.7 ± 1.1 0.4 ± 0.7*
 1-month weight gain (kg) 1.8 ± 1.8 0.6 ± 1.7*** 1.9 ± 1.8 0.8 ± 1.6***
 3-months weight gain (kg) 4.0 ± 3.0 1.6 ± 3.2*** 4.2 ± 3.1 2.0 ± 3.2***
1-year follow-up
 Age (years) 15.9 ± 1.6 16.3 ± 1.8 16.0 ± 1.6 16.1 ± 1.8
 BMISDS 0.06 ± 0.90 0.01 ± 0.96 0.17 ± 0.85 −0.11 ± 0.97*
 Weight gain (kg) 6.9 ± 4.6 3.9 ± 6.7*** 7.1 ± 4.4 4.5 ± 6.4**
 Weight suppression (SDS) 0.50 ± 0.83 0.95 ± 0.95** 0.46 ± 0.74 0.88 ± 1.01***
 EDE-Q global score 0.7 ± 0.6 3.5 ± 1.0*** 0.7 ± 0.7 2.8 ± 1.5***
 ED diagnoses (no ED/AN/BN/OSFEDr) 102/1/1/26 (78/1/1/20%) 4/3/2/62 (6/4/3/87%)*** 125/0/0/0 (100/0/0/0%) 0/4/3/88 (0/4/3/93%)***
 MADRS-S 7 ± 7 21 ± 10*** 7 ± 8 17 ± 11***
 Depression (n) 8 (6%) 24 (34%)*** 7 (7%) 25 (27%)***
 Neuropsychiatric diagnoses (n) 13 (10%) 17 (24%)* 12 (11%) 19 (20%)*
  1. Values are means ± standard deviations. Significance of difference between recovered adolescents (EDE-Q < 2.0 or absence of an ED) and those with a persisting disease: *p < 0.05, **p < 0.01, ***p < 0.001 by Student’s t-test for continuous data and Chi-square test for categorical data
  2. ED eating disorder, BMI body mass index, SDS standard deviation score, EDE-Q eating disorders examination-questionnaire, MADRS-S Montgomery-Åsberg depression rating scale-self report, AN anorexia nervosa, BN (subthreshold) bulimia nervosa, OSFEDr other specified feeding and eating disorders-restrictive subtype