Do some anxiety disorders belong to the prodrome of bipolar disorder? A clinical study combining retrospective and prospective methods to analyse the relationship between anxiety disorder and bipolar disorder from the perspective of biorhythms

Table 4 YMRS, HAMA and YBOCS scores of the atypical and anxiety groups

Variables	Atypical (n1 = 63, n2 = 6) Mean ± SD	Anxiety (n1 = 111, n2 = 27) Mean ± SD	t
YMRS-4 (sleep)	0.67 ± 0.90	0.03 ± 0.16	4.569^***
YMRS-5 (irritability)	0.86 ± 0.95	0.14 ± 0.48	4.698^***
YMRS-7 (thought form)	0.05 ± 0.22	0	2.340^*
YMRS-8 (thought content)	0.14 ± 0.35	0	4.214^***
YMRS-9 (aggressive behaviour)	0.05 ± 0.22	0	2.340^*
YMRS-10 (appearance)	0.05 ± 0.22	0	2.340^*
Total score of YMRS	1.81 ± 1.94	0.16 ± 0.49	5.433^***
HAMA-5 (cognitive function)	1.90 ± 0.53	1.54 ± 0.83	2.646^**
HAMA-6 (depressed mood)	2.05 ± 1.06	1.46 ± 0.86	3.534^**
HAMA-8 (sensory symptoms)	0.67 ± 1.00	1.35 ± 1.24	−3.200^**
HAMA-13 (ANS symptoms)	1.14 ± 0.65	1.46 ± 0.89	−2.099^*
HAMA-14 (performance)	1.57 ± 0.67	1.97 ± 0.49	−3.546^**
Somatic anxiety factor	4.14 ± 3.82	5.76 ± 3.46	−2.503^*
Total score of YBOCS	22.50 ± 4.95	19.22 ± 2.95	2.052^*

*P < 0.05, **P < 0.01, ***P < 0.001
ANS represents the autonomic nervous system, n1 represents the number of subjects who completed the YMRS and the HAMA, n2 represents the number of subjects who completed the YBOCS

ISSN: 1471-244X