Do some anxiety disorders belong to the prodrome of bipolar disorder? A clinical study combining retrospective and prospective methods to analyse the relationship between anxiety disorder and bipolar disorder from the perspective of biorhythms

Table 5 The reduction rates of HAMA and YBOCS scores in the atypical and anxiety groups

Variables	Anxiety (n1 = 111, n2 = 27)			Atypical (n1 = 63, n2 = 6)					χ ²
Variables	Enrolment	3 months later	Reduction rate^a	Enrolment	3 months later	6 months later	Reduction rate^b	Reduction rate^c	χ ²
Total HAMA score	16.92 ± 3.26	5.58 ± 1.46**	67.02	16.13 ± 3.98	14.82 ± 3.15	5.34 ± 1.21	8.12	66.90	0.659
Total YBOCS score	19.22 ± 2.95	8.36 ± 2.69**	56.50	22.50 ± 4.95	20.69 ± 4.35	9.58 ± 2.87	8.04	57.42	0.852

**P < 0.01
n1 represents the number of subjects who completed the HAMA, n2 represents the number of subjects who completed the YBOCS, ^arepresents the reduction rate between enrolment and 3 months later in the anxiety group; ^brepresents the reduction rate between enrolment and 3 months later in the atypical group; ^crepresents the reduction rate between enrolment and 6 months later in the atypical group; the value of χ ²represents the comparison between reduction rate a and reduction rate c

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