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Table 2 Linear regression models for the association between depression and antidepressant use with IL6 methylation at CpG 2

From: Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression

Characteristics

Unadjusted associationsa

Adjusted associations

Multivariate adjusted model

 

β (SE)

p

β (SE)

p

β (SE)

p

Depression

−0.018 (0.009)

0.033

−0.024 (0.009)

0.006

−0.028 (0.009)

0.003

Antidepressants

0.032 (0.019)

0.090

0.046 (0.019)

0.015

0.046 (0.019)

0.017

Female Sex

    

0.003 (0.008)

0.71

Living alone

    

0.010 (0.010)

0.29

Cognitive impairment

    

0.004 (0.019)

0.83

  1. β the beta coefficient from the linear regression model, SE standard error
  2. aDepression and antidepressant use considered independently in separate models