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Table 3 Significantly different clusters of gray matter density identified by post hoc analysis between SZ-CD, SZ-NCD, and HCs

From: Gray matter morphological anomalies in the cerebellar vermis in first-episode schizophrenia patients with cognitive deficits

 

MNI coordinates

(mm, mm, mm)

Contrasts

Cluster size

Brain regions

T value

Z value

X

Y

Z

SZ-CD

vs

HCs

25,102

Cerebellum

vermis, tonsil

4.43

4.04

−11

−57

−70

3598

Right STG

3.29

3.11

68

−8

6

Left PUT

2.97

2.84

−26

8

2

SZ-NCD vs

HCs

8879

Left CL

5.02

4.49

−11

21

−2

Left PHG

4.34

3.97

−21

−5

−27

5924

Left Cerebellum

3.41

3.22

−42

−59

−48

SZ-CD

vs

SZ-NCD

8113

Left SMA

4.54

4.13

−6

−20

59

Left PreCG

3.4

3.21

−26

−18

60

Right PreCG

4.0

3.7

41

−15

36

3383

Cerebellum

vermis, tonsil

3.67

3.44

8

−44

−2

  1. X, Y, Z, coordinates of peak locations in the MNI space
  2. STG superior temporal gyrus, PUT putamen, CL caudate lobe, PHG parahippocampal gyrus, SMA, supplementary motor area, PreCG precentral gyrus, MNI Montreal Neurological Institute, SZ-CD schizophrenia with cognitive deficits, SZ-NCD schizophrenia with no cognitive deficits
  3. P < 0.05, corrected for multiple comparisons, cluster size >3152 voxels (SZ-CD vs HCs), cluster size >3369 voxels (SZ-NCD vs HCs), cluster size > 3380 voxels (SZ-CD vs SZ-NCD)