Skip to main content

Table 4 Spearman rank correlation analysis between 5HTR2A mRNA levels and scores on psychometric scales in patients with schizophrenic disorder during the administration of antipsychotics

From: Potential diagnostic markers of olanzapine efficiency for acute psychosis: a focus on peripheral biogenic amines

Group of patients    Treated with haloperidol Treated with olanzapine
Indicator of peripheral biogenic amine    5HTR2A mRNA levels
Before treatment
5HTR2A mRNA levels
Before treatment
Scores of psychometric scales: 0.524* 0.653**
Administration of antipsychotic Before treatment Total PANSS
Positive PANSS 0.114 0.035
Negative PANSS 0.237 0.329
General psychopathology PANSS 0.239 0.217
CGI-S 0.030 0.033
Day 14 Total PANSS −0.018 0.686**
Positive PANSS 0.033 0.323
Negative PANSS 0.080 0.332
General psychopathology PANSS 0.011 0.379*
CGI-S 0.067 0.338
Day 28 Total PANSS 0.061 0.715**
Positive PANSS −0.092 0.466*
Negative PANSS −0.031 0.411*
General psychopathology PANSS 0.146 0.392*
CGI-S −0.095 0.402*
  1. *p < 0.05, **p < 0.001