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Table 5 Spearman rank correlation analysis between the blood serum dopamine level and scores on extrapyramidal symptom scales in patients with schizophrenic disorder during the administration of antipsychotics

From: Potential diagnostic markers of olanzapine efficiency for acute psychosis: a focus on peripheral biogenic amines

Indicator of peripheral biogenic amine

  

Blood serum dopamine level

  

Blood serum dopamine level

  

Group of patients

  

Treated with haloperidol

Treated with olanzapine

Administration of antipsychotic

Before treatment

Day 14

Day 28

Before treatment

Day 14

Day 28

Scores on the extrapyramidal symptom scales:

−0.149

  

−0.315

  

Administration of antipsychotic

Before treatment

SAS

ESRS

−0.500

  

−0.316

  

Day 14

SAS

 

0.292

  

−0.465*

 

ESRS

 

0.175

  

−0.475*

 

Day 28

SAS

  

0.037

  

−0.609**

ESRS

  

0.076

  

−0.609**

  1. *p < 0.05, **p < 0.001