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Table 4 Outcomes at baseline, 12 and 15 months (all 15 month outcomes discounted)

From: Randomised controlled trial to improve health and reduce substance use in established psychosis (IMPaCT): cost-effectiveness of integrated psychosocial health promotion

  Intervention
n = 213
Control
n = 193
Unadjusted mean differenceb 95% CIb Adjusted mean differencec 95% CIc
  valid n Mean SD valid n Mean SD     
Baseline
 SF-36 mental component score 213 41.37 13.26 193 42.25 11.81 −0.88 −3.44 to 1.68 −0.26 −1.55 to 1.02
 SF-36 physical component score 213 45.83 10.94 193 47.04 9.26 −1.20 −3.31 to 0.91 −0.60 −1.72 to 0.52
 SF-36 utility 210 0.69 0.16 192 0.71 0.14 −0.02 −0.05 to 0.02 0.00 −0.01 to 0.01
 EQ-5D-3 L utility 211 0.76 0.31 193 0.79 0.28 −0.02 −0.08 to 0.04 0.01 −0.04 to 0.06
12 months
 SF-36 mental component score 160 43.18 13.31 158 44.09 13.47 −0.91 −3.94 to 2.11 −0.05 −2.64 to 2.55
 SF-36 physical component score 160 46.76 11.23 158 49.02 10.55 −2.27 −4.74 to 0.21 −1.45 −3.56 to 0.66
 SF-36 utility 158 0.70 0.16 155 0.71 0.15 −0.02 −0.05 to 0.02 −0.00 −0.03 to 0.02
 EQ-5D-3 L utility 159 0.80 0.25 156 0.80 0.28 0.00 −0.06 to 0.06 0.03 −0.03 to 0.08
15 months
 SF-36 mental component score 152 42.47 13.58 149 45.01 13.65 −2.54 −6.00 to 0.92 −0.80 −3.66 to 2.06
 SF-36 physical component score 152 47.25 11.62 149 48.54 9.88 −1.29 −4.02 to 1.44 −0.68 −3.01 to 1.65
 SF-36 utility 149 0.66 0.14 148 0.70 0.15 −0.03a −0.07 to −0.00a −0.02 −0.05 to 0.01
 SF-36 based QALY gain 134 0.17 0.03 139 0.17 0.09 −0.01 −0.01 to 0.00 −0.00 −0.01 to 0.00
 EQ-5D-3 L utility 152 0.77 0.24 149 0.80 0.25 −0.02 −0.09 to 0.04 0.00 −0.06 to 0.06
 EQ-5D-3 L based QALY gain 137 0.19 0.05 140 0.20 0.06 −0.00 −0.02 to 0.01 0.00 −0.01 to 0.02
  1. aConfidence interval excludes zero
  2. bAdjusting for clustering of care coordinator
  3. cIncludes covariates for baseline: SF-36 mental component score, SF-36 physical component score, EQ-5D-3 L utility, SF-36 utility, gender, age, ethnicity, place of birth and borough, plus clustering for care coordinator