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Table 3 Receiver-operating Characteristics for Generalized Anxiety Disorder using Different Thresholds of the Anxiety Subscale of the Hospital Anxiety and Depression Scale (HADS-A)

From: Does presence of metabolic syndrome impact anxiety and depressive disorder screening results in middle aged and elderly individuals? A population based study

Thresholds n (%) Sensitivity, % (95% CI) Specificity, % (95% CI) PPV, % (95% CI) NPV, % (95% CI) Accuracy, % (95% CI) AUC (95% CI)
All study participants, n = 1115
  ≥ 6 661 (59) 98 (95–99) 53 (50–56) 40 (36–44) 99 (97–100) 64 (61–67) 0.93 (0.91–0.94)
  ≥ 7 554 (50) 96 (92–98) 65 (62–68) 46 (42–51) 98 (96–99) 72 (70–75)  
  ≥ 8 456 (41) 94 (90–96) 76 (73–79) 55 (51–60) 97 (96–98) 80 (78–82)  
  ≥ 9 373 (33) 87 (82–90) 84 (81–86) 63 (57–67) 95 (93–97) 84 (82–86)  
  ≥ 10 301 (27) 79 (73–83) 90 (87–91) 70 (65–76) 93 (91–95) 87 (85–89)  
With Metabolic syndrome only (WHO definition), n = 384
  ≥ 6 242 (63) 98 (93–100) 52 (46–58) 47 (41–54) 99 (95–100) 66 (61–71) 0.95 (0.92–0.97)
  ≥ 7 205 (53) 97 (92–100) 66 (60–71) 55 (48–62) 98 (95–100) 75 (71–79)  
  ≥ 8 171 (45) 95 (89–98) 77 (72–82) 64 (57–71) 97 (94–99) 83 (78–86)  
  ≥ 9 146 (38) 91 (83–95) 85 (80–89) 72 (64–79) 95 (92–98) 86 (83–90)  
  ≥ 10 119 (31) 84 (75–90) 92 (88–95) 82 (73–88) 93 (89–96) 89 (86–92)  
Without Metabolic syndrome only (WHO definition), n = 731
  ≥ 6 419 (57) 98 (94–100) 53 (49–58) 36 (31–41) 99 (97–100) 63 (59–66) 0.91 (0.89–0.94)
  ≥ 7 349 (48) 94 (89–97) 65 (60–68) 41 (36–47) 98 (95–99) 71 (67–74)  
  ≥ 8 285 (39) 93 (87–96) 75 (72–79) 50 (44–56) 98 (95–99) 79 (76–82)  
  ≥ 9 227 (31) 84 (77–89) 83 (80–86) 56 (50–63) 95 (93–97) 83 (80–86)  
  ≥ 10 182 (25) 75 (67–82) 88 (85–91) 63 (56–70) 93 (91–95) 86 (83–88)  
  1. PPV positive predictive value, NPV negative predictive value, AUC area under the receiver operating curve, CI confidence interval
  2. Optimal thresholds in bold