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Table 2 Sociodemographic characteristics at enrollment of long-acting injectable antipsychotic therapy vs oral antipsychotic therapy usersa

From: The Research and Evaluation of Antipsychotic Treatment in Community Behavioral Health Organizations, Outcomes (REACH-OUT) study: real-world clinical practice in schizophrenia

 

LAI APT

 
 

Total

n = 599

New User

n = 214

Continuous User

n = 385

Oral APT

n = 281

Age, years

 N

566

200

366

265

 Mean (SD)

41.1 (12.42)

39.4 (12.01)

42.0 (12.56)

42.1 (13.49)

P value (LAI vs oral)

0.268

0.021

0.921

 

Sex, n (%)

 N

585

207

378

275

 Male

424 (72.5)

155 (74.9)

269 (71.2)

181 (65.8)

 Female

161 (27.5)

52 (25.1)

109 (28.8)

94 (34.2)

P value (LAI vs oral)

0.054

0.031

0.144

 

Race, n (%)

 N

577

203

374

271

 White

292 (50.6)

85 (41.9)

207 (55.3)

133 (49.1)

 Black or African American

188 (32.6)

90 (44.3)

98 (26.2)

90 (33.2)

 Asian, Native Hawaiian, or other Pacific Islander

9 (1.6)

3 (1.5)

6 (1.6)

1 (0.4)

 American Indian or Alaska Native

12 (2.1)

3 (1.5)

9 (2.4)

8 (3.0)

 Multiracial/Other

76 (13.2)

22 (10.8)

54 (14.4)

39 (14.4)

P value (LAI vs oral)

0.645

0.092

0.276

 

Ethnicity (Spanish, Hispanic, Latino), n (%)

 N

576

200

376

274

 No

494 (85.8)

174 (87.0)

320 (85.1)

202 (73.7)

 Yes

82 (14.2)

26 (13.0)

56 (14.9)

72 (26.3)

P value (LAI vs oral)

<0.001

<0.001

<0.001

 

Education, n (%)

 N

584

207

377

272

 8th grade or less

56 (9.6)

25 (12.1)

31 (8.2)

45 (16.5)

 Some high school, did not graduate/get GED

161 (27.6)

56 (27.1)

105 (27.9)

70 (25.7)

 High school degree/GED

222 (38.0)

70 (33.8)

152 (40.3)

101 (37.1)

 Some college or college degree

145 (24.8)

56 (27.1)

89 (23.6)

56 (20.6)

P value (LAI vs oral)

0.030

0.234

0.019

 

Military service, n (%)

 N

581

206

375

273

 No

535 (92.1)

187 (90.8)

348 (92.8)

255 (93.4)

 Yes

46 (7.9)

19 (9.2)

27 (7.2)

18 (6.6)

P value (LAI vs oral)

0.577

0.309

0.868

 

Marital status, n (%)

 N

584

206

378

275

 Single, never married

413 (70.7)

149 (72.3)

264 (69.8)

160 (58.2)

 Married

37 (6.3)

9 (4.4)

28 (7.4)

27 (9.8)

 Widowed

13 (2.2)

2 (1.0)

11 (2.9)

8 (2.9)

 Divorced/Separated

108 (18.5)

41 (19.9)

67 (17.7)

72 (26.2)

 Nonmarried committed relationship

13 (2.2)

5 (2.4)

8 (2.1)

8 (2.9)

P value (LAI vs oral)

0.010

0.012

0.035

 

Living situation, n (%)

 N

586

207

379

273

 Clinical facilityb

10 (1.71)

6 (2.90)

4 (1.06)

2 (0.73)

 Supervised group living (generally long-term)

67 (11.4)

15 (7.2)

52 (13.7)

7 (2.6)

 Transitional group home (halfway/quarterway house)

3 (0.5)

1 (0.5)

2 (0.5)

3 (1.1)

 Family foster care

1 (0.2)

0 (0.0)

1 (0.3)

1 (0.4)

 Cooperative apartment

20 (3.4)

8 (3.9)

12 (3.2)

9 (3.3)

 Boarding home

47 (8.0)

27 (13.0)

20 (5.3)

17 (6.2)

 Private house or apartment

410 (70.0)

139 (67.1)

271 (71.5)

212 (77.7)

 Other

28 (4.8)

11 (5.3)

17 (4.5)

22 (8.1)

P value (LAI vs oral)

0.001

0.036

<0.001

 

Medicare, n (%)

 N

575

202

373

266

 No

275 (47.8)

106 (52.5)

169 (45.3)

166 (62.4)

 Yes

300 (52.2)

96 (47.5)

204 (54.7)

100 (37.6)

P value (LAI vs oral)

<0.001

0.036

<0.001

 

Medicaid or medical assistance, n (%)

 N

574

202

372

270

 No

140 (24.4)

61 (30.2)

79 (21.2)

101 (37.4)

 Yes

434 (75.6)

141 (69.8)

293 (78.8)

169 (62.6)

P value (LAI vs oral)

<0.001

0.115

<0.001

 

Private health insurance, n (%)

 N

573

200

373

273

 No

535 (93.4)

183 (91.5)

352 (94.4)

248 (90.8)

 Yes

38 (6.6)

17 (8.5)

21 (5.6)

25 (9.2)

P value (LAI vs oral)

0.204

0.872

0.088

 

Veterans or military medical benefits, n (%)

 N

580

203

377

273

  No

569 (98.1)

200 (98.5)

369 (97.9)

271 (99.3)

  Yes

11 (1.9)

3 (1.5)

8 (2.1)

2 (0.7)

  P value (LAI vs oral)

0.242

0.646

0.202

 
  1. APT antipsychotic therapy, GED general education diploma, LAI long-acting injectable (includes paliperidone palmitate long-acting injectable and risperidone long-acting injectable), SD standard deviation
  2. aAll subjects with schizophrenia. bIncludes hospital, skilled nursing facility (24-h nursing), and intermediate care facility (<24-h nursing)