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Table 4 Patient-reported outcomes at enrollment

From: The Research and Evaluation of Antipsychotic Treatment in Community Behavioral Health Organizations, Outcomes (REACH-OUT) study: real-world clinical practice in schizophrenia

  LAI APT  
Patient-Reported Outcome Assessment Total
n = 599
New Users
n = 214
Continuous Users
n = 385
Oral APT
n = 281
Attitude toward medication Mean (SD) DAI-10 score 6.0 (3.66) 5.7 (3.66) 6.1 (3.67) 4.5 (4.03)
Medication satisfaction Mean (SD) MSQ score 5.8 (1.40) 5.6 (1.49) 5.9 (1.34) 5.2 (1.44)
“Very satisfied,” % (n/N) 35.0 (200/572) 30.2 (60/199) 37.5 (140/373) 13.8 (37/268)
Quality of life Mean (SD) QOLI score
 General life satisfaction 4.8 (1.30) 4.7 (1.39) 4.9 (1.25) 4.3 (1.52)
 Daily activities 4.8 (1.13) 4.7 (1.22) 4.9 (1.07) 4.3 (1.29)
 Family contact 4.9 (1.44) 4.7 (1.56) 5.0 (1.36) 4.5 (1.59)
 Social relations 4.9 (1.20) 4.8 (1.29) 4.9 (1.14) 4.5 (1.22)
 Finance 3.9 (1.50) 3.6 (1.57) 4.0 (1.45) 3.3 (1.71)
 Safety 5.0 (1.26) 5.0 (1.29) 5.0 (1.25) 4.5 (1.58)
 Health 4.6 (1.28) 4.5 (1.39) 4.6 (1.22) 4.0 (1.36)
Patient-caregiver engagement Mean (SD), frequency of interaction in the past 4 weeks
 Talk to or email a member of family 3.4 (1.53) 3.6 (1.54) 3.3 (1.52) 3.3 (1.60)
 Get together with family 2.9 (1.49) 2.9 (1.54) 2.8 (1.46) 2.8 (1.50)
 Visit with a friend 2.6 (1.44) 2.4 (1.31) 2.7 (1.50) 2.3 (1.39)
 Talk to or email a friend who does not live with you 2.6 (1.49) 2.6 (1.47) 2.6 (1.50) 2.5 (1.55)
 Plan ahead to do something with another person 2.0 (1.13) 1.9 (1.08) 2.0 (1.15) 1.9 (1.13)
 Spend time with someone more than a friend 2.1 (1.53) 2.1 (1.52) 2.1 (1.53) 2.3 (1.68)
Patient functioning  Mean PSP total score 61.6 59.6 62.7 57.5
  1. APT antipsychotic therapy, DAI-10 Drug Attitude Inventory 10-item scale, LAI long-acting injectable (includes paliperidone palmitate long-acting injectable and risperidone long-acting injectable), MSQ Medication Satisfaction Questionnaire, PSP Personal and Social Performance scale, QOLI Lehman’s Quality of Life Interview, SD standard deviation