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Table 3 Talairach Coordinates and Z-scores of areas with rCBF changes in MDD patients

From: Towards characterizing the regional cerebral perfusion in evaluating the severity of major depression disorder with SPECT/CT

Number of clusters

Co-ordinates

Region

Z-score

(PFWE-corr < 0.05)

X

Y

Z

INC: 2

-32

-80

-10

left occipital lobe (B17、B18、B19、B37)

5.91

-8

-82

-8

5.43

36

-70

-14

right occipital lobe (B17、B18、B19、B37)

4.87

DEC:4

38

14

-24

right temporal lobe (B22、B38、B41、B42), right insula and right frontal lobe (B11、B44、B45、B47)

6.07

42

16

-12

5.30

46

6

-24

5.09

-32

4

-4

left insula, left frontal lobe (B11、B44、B45、B47), left temporal lobe (B22、B38、B41、B42) and aleft anterior cingulate cortex (B24、B33)

5.30

-38

-2

-2

5.07

20

22

0

right frontal lobe (B4、B6、B10、B11、B44、B45、B46、B47), right temporal lobe (B21、B22、B38、B41、B42), right insula and aright anterior cingulate cortex (B24、B33)

4.50

8

22

-20

right frontal lobe (B4、B6、B10、B46)

4.40

  1. L Left, R Right, DEC The decreased rCBF areas, INC the increased rCBF areas, rCBF Regional cerebral blood flow, PFWE-corr p-value with FEW correction in %, FEW family-wise error
  2. a only exist in P < 0.001