From: Anxiety and depression in primary Sjögren’s syndrome: a cross-sectional study
Clinical characteristics | pSS(n = 160) | Controls(n = 170) | t/x 2 | p |
---|---|---|---|---|
Age, mean ± sd years | 51.09 ± 12.11 | 50.14 ± 11.22 | 0.32 | 0.446 |
Gender, female, no. (%) | 152(95) | 162(95.3) | 0.02 | 0.901 |
Marital status, no. (%) | 3.50 | 0.061 | ||
Married | 151 (94.4) | 167 (98.2) | ||
Other marital status | 9 (5.6) | 3 (1.8) | ||
Education, years | 12.19 ± 4.33 | 12.03 ± 4.62 | 0.33 | 0.740 |
Employment status, no. (%) | 1.28 | 0.259 | ||
Employed | 71(44.4) | 86(50.6) | ||
Unemployed | 89(55.6) | 84(49.4) | ||
Income/person/year, yuan, no. (%) | 1.65 | 0.569 | ||
< 15,000 yuan | 55 (34.37) | 49(28.8) | ||
15,000-33,000 yuan | 49 (30.63) | 62(36.5) | ||
≥ 33,000 yuan | 56(35) | 59(34.7) | ||
Type of medical insurance, n (%) | 4.33 | 0.115 | ||
With basic medical insurance | 146(91.3) | 164(96.5) | ||
Self-pay | 13(8.1) | 6(3.5) | ||
Other | 1(0.6) | 0(0) | ||
HADS-A, mean ± sd | 6.52 ± 4.06 | 3.02 ± 2.78 | 9.08 | 0.000 |
HADS-D, mean ± sd | 6.71 ± 4.32 | 3.87 ± 2.80 | 7.05 | 0.000 |
Disease duration, mean ± sd years | 4.498 ± 5.44 | – | – | |
OSDI, mean ± sd | 29.14 ± 25.12 | – | – | |
VAS pain (range 0–10), mean ± sd | 2.36 ± 2.65 | – | – | |
ESR, mean ± sd mm/h | 30.65 ± 24.13 | – | – | |
RF positivity, yes, no. (%) | 51(49.5) | – | – | |
Hospitalization, yes, n (%) | 108(67.5) | – | – | |
Family history, yes, n (%) | 23(14.4) | – | – | |
Comorbid conditions, yes, n (%) | 102(63.75) | – | – | |
ESSDAI | 9.6 ± 7.3 | – | – | |
ESSPRI | 4.53 ± 1.95 | – | – | |
FSS | 3.89 ± 1.59 | 1.64 ± 0.89 | 15.76 | 0.000 |
OHIP-14 | 12.89 ± 11.38 | 3.41 ± 4.92 | 9.29 | 0.000 |
MDADI | 72.33 ± 18.83 | – | – | |
IgG (g/L) | 18.93 ± 6.65 | – | – | |
C3 (g/L) | 0.81 ± 0.27 | – | – | |
C4 (g/L) | 0.18 ± 0.65 | – | – | |
ANA ≥1: 320 | 96(91.4) | – | – | |
Anti-SSA ≥ 200 RU/mL | 85(81) | – | – | |
Anti-SSB ≥ 20 RU/mL | 53(50.5) | – | – |