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Table 1 summarizes the demographic and clinical characteristics of the participants in the study

From: Anxiety and depression in primary Sjögren’s syndrome: a cross-sectional study

Clinical characteristics

pSS(n = 160)

Controls(n = 170)

t/x 2

p

Age, mean ± sd years

51.09 ± 12.11

50.14 ± 11.22

0.32

0.446

Gender, female, no. (%)

152(95)

162(95.3)

0.02

0.901

Marital status, no. (%)

  

3.50

0.061

 Married

151 (94.4)

167 (98.2)

  

 Other marital status

9 (5.6)

3 (1.8)

 

Education, years

12.19 ± 4.33

12.03 ± 4.62

0.33

0.740

Employment status, no. (%)

  

1.28

0.259

 Employed

71(44.4)

86(50.6)

  

 Unemployed

89(55.6)

84(49.4)

 

Income/person/year, yuan, no. (%)

  

1.65

0.569

  < 15,000 yuan

55 (34.37)

49(28.8)

  

 15,000-33,000 yuan

49 (30.63)

62(36.5)

 

  ≥ 33,000 yuan

56(35)

59(34.7)

 

Type of medical insurance, n (%)

  

4.33

0.115

 With basic medical insurance

146(91.3)

164(96.5)

  

 Self-pay

13(8.1)

6(3.5)

 

 Other

1(0.6)

0(0)

 

HADS-A, mean ± sd

6.52 ± 4.06

3.02 ± 2.78

9.08

0.000

HADS-D, mean ± sd

6.71 ± 4.32

3.87 ± 2.80

7.05

0.000

Disease duration, mean ± sd years

4.498 ± 5.44

 

OSDI, mean ± sd

29.14 ± 25.12

 

VAS pain (range 0–10), mean ± sd

2.36 ± 2.65

 

ESR, mean ± sd mm/h

30.65 ± 24.13

 

RF positivity, yes, no. (%)

51(49.5)

 

Hospitalization, yes, n (%)

108(67.5)

 

Family history, yes, n (%)

23(14.4)

 

Comorbid conditions, yes, n (%)

102(63.75)

 

ESSDAI

9.6 ± 7.3

 

ESSPRI

4.53 ± 1.95

 

FSS

3.89 ± 1.59

1.64 ± 0.89

15.76

0.000

OHIP-14

12.89 ± 11.38

3.41 ± 4.92

9.29

0.000

MDADI

72.33 ± 18.83

 

IgG (g/L)

18.93 ± 6.65

 

C3 (g/L)

0.81 ± 0.27

 

C4 (g/L)

0.18 ± 0.65

 

ANA ≥1: 320

96(91.4)

 

Anti-SSA ≥ 200 RU/mL

85(81)

 

Anti-SSB ≥ 20 RU/mL

53(50.5)

 

  1. VAS visual analog scale, ESR erythrocyte sedimentation rate, RF rheumatoid factor, HADS hospital anxiety and depression scale, HADS-A hospital anxiety scale, HADS-D hospital depression scale, ESSDAI EULAR Sjögren’s syndrome disease activity index, ANA antinuclear antibodies, IgG Immunoglobulin G, C3 complement C3, C4 complement C4, OSDI the ocular surface disease index