From: Anxiety and depression in primary Sjögren’s syndrome: a cross-sectional study
Clinical characteristics | non-anxiety | Anxiety | p | non-depression | depression | p |
---|---|---|---|---|---|---|
Age, mean ± sd yearsa | 50.08 ± 11.90 | 51.44 ± 12.90 | 0.508 | 49.69 ± 11.96 | 51.12 ± 12.68 | 0.228 |
Gender, female, no. (%)b | 100(94.3) | 55 (96.3) | 0.878 | 97(96) | 55 (93.2) | 0.679 |
Marital status, no. (%)b | 1.000 | 0.401 | ||||
Married | 100 (94.3) | 51 (94.4) | 97 (96) | 54 (91.5) | ||
Other marital status | 6 (5.7) | 3 (5.6) | 4 (4) | 5 (8.5) | ||
Education, years, no. (%)a | 12.43 ± 4.42 | 11.72 ± 4.16 | 0.327 | 13.00 ± 3.96 | 10.81 ± 4.62 | 0.002* |
Employment status, no. (%)b | 0.064 | 0.049* | ||||
Employed | 53 (50) | 18 (33.3) | 51 (50.5) | 20 (33.9) | ||
Unemployed | 53 (50) | 36 (66.7) | 50 (49.5) | 39 (66.1) | ||
Income/person/year, yuan, no. (%)b | 0.423 | 0.094 | ||||
< 15,000 yuan | 34 (32.1) | 21 (38.9) | 31 (30.7) | 24 (40.7) | ||
15,000-33,000 yuan | 36 (34) | 13 (24.1) | 37 (36.6) | 12 (20.3) | ||
≥ 33,000 yuan | 36 (34) | 20 (37) | 33 (32.7) | 23 (39) | ||
Type of medical insurance, n (%)b | 0.749 | 0.660 | ||||
With basic medical insurance | 96 (90.6) | 50 (92.6) | 91 (90.1) | 55 (93.2) | ||
Self-pay | 9 (8.5) | 4 (7.4) | 9 (8.9) | 4 (6.8) | ||
Other | 1 (0.9) | 0 (0) | 1 (1) | 0 (0) | ||
Disease duration, mean ± sd yearsa | 4.48 ± 5.61 | 4.53 ± 5.15 | 0.957 | 4.30 ± 4.72 | 4.83 ± 6.53 | 0.557 |
VAS pain (range 0–10), mean ± sda | 2.12 ± 2.51 | 2.83 ± 2.98 | 0.127 | 2.35 ± 1.95 | 3.07 ± 2.99 | 0.016* |
ESR, mean ± sd mm/ha | 28.10 ± 21.38 | 35.87 ± 28.47 | 0.085 | 27.10 ± 20.04 | 36.78 ± 29.10 | 0.027* |
OSDI, mean ± sda | 25.07 ± 22.40 | 37.15 ± 28.28 | 0.008* | 23.82 ± 20.81 | 38.26 ± 29.14 | 0.001* |
RF positivity, yes, no. (%)b | 29 (46) | 22 (55) | 0.422 | 30 (49.2) | 21 (50) | 1.000 |
Hospitalization, yes, n (%)b | 68 (64.2) | 40 (74.1) | 0.218 | 68 (67.3) | 40 (67.8) | 1.000 |
Family history, yes, n (%)b | 15 (14.2) | 8 (14.8) | 1.000 | 17 (16.8) | 6 (10.2) | 0.351 |
Comorbid conditions, yes, n (%)b | 66 (62.3) | 36 (66.7) | 0.607 | 61 (60.4) | 41 (69.5) | 0.307 |
ESSDAIa | 9.16 ± 7.73 | 10.48 ± 6.37 | 0.281 | 8.73 ± 7.35 | 11.10 ± 7.03 | 0.047* |
IgG (g/L)a | 19.05 ± 6.72 | 18.72 ± 6.60 | 0.806 | 18.99 ± 6.54 | 18.84 ± 6.85 | 0.909 |
C3 (g/L)a | 0.80 ± 0.26 | 0.82 ± 0.28 | 0.781 | 0.80 ± 0.24 | 0.82 ± 0.30 | 0.632 |
C4 (g/L)a | 0.18 ± 0.07 | 0.17 ± 0.06 | 0.627 | 0.18 ± 0.66 | 0.17 ± 0.06 | 0.552 |
ANA ≥1: 320b | 61 (91) | 35 (92.1) | 1.000 | 60 (93.8) | 36 (87.8) | 0.481 |
Anti-SSA ≥ 200 RU/mLb | 54 (80.6) | 31 (81.6) | 1.000 | 50 (78.1) | 35 (85.4) | 0.449 |
Anti-SSB ≥ 20 RU/mLb | 32 (47.8) | 21 (55.3) | 0.544 | 29 (45.3) | 24 (58.5) | 0.231 |