Health-related quality of life in multiple sclerosis: temperament outweighs EDSS

Table 2 Linear regression analysis is showing the effect of temperament types on MusiQol Global Index Score (N = 81)

	R²	effect (CI)	p-value	Adj. p-value
Global Index Score	0.309		–	–
Depressive T	0.403	−2.2 (−3.5; −0.9)	0.001	0.005
Cyclothymic T	0.425	−3.0 (−4.5;-1.4)	< 0.001	0.002
Hyperthymic T	0.458	1.0 (0.6;1.4)	< 0.001	< 0.001
Irritative T	0.310	−0.3 (−1.7;1.2)	0.717	1.0
Anxious T	0.319	−1.0 (−2.9;0.9)	0.293	0.880

effect: regression coefficient quantifying the effect of a 20% increase in the respective temperament score (except hyperthymic temperament: quantifying the effect of a unit increase in the temperament score); CI: 95% confidence interval; adj. p-value: adjusted for testing five temperaments (Bonferroni-Holm method). T: Temperament

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