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Table 3 Associations between the ABCB1 genotype and ANS activity

From: Effects of ABCB1 gene polymorphisms on autonomic nervous system activity during atypical antipsychotic treatment in schizophrenia

 

rs1045642

rs1128503

rs2032582

rs2235048

C/C

C/T, T/T

P

T/T

C/T, C/C

P

G/G

G/A•T

A•T/A•T

P

T/T

C/C, C/T

P

Risperidone (n = 89)

 N

31

58

 

37

52

 

14

75

 

31

58

 

  lnLF (ms2)

4.38 ± 1.16

4.51 ± 1.25

.629

4.40 ± 1.15

4.51 ± 1.20

.693

4.59 ± 1.02

4.44 ± 1.26

.675

4.38 ± 1.16

4.51 ± 1.25

.629

  lnHF (ms2)

3.94 ± 1.38

3.99 ± 1.68

.881

4.02 ± 1.62

3.94 ± 1.55

.831

4.35 ± 1.16

3.91 ± 1.63

.339

3.94 ± 1.38

3.99 ± 1.68

.881

  lnTP (ms2)

5.00 ± 1.13

5.10 ± 1.31

.721

5.05 ± 1.29

5.08 ± 1.23

.898

5.26 ± 0.96

5.03 ± 1.26

.529

5.00 ± 1.13

5.10 ± 1.31

.721

Olanzapine (n = 69)

 N

20

49

 

35

34

 

15

54

 

20

49

 

  lnLF (ms2)

4.15 ± 1.22

4.40 ± 1.09

.421

4.41 ± 1.02

4.22 ± 1.23

.489

4.19 ± 1.06

4.36 ± 1.15

.605

4.15 ± 1.22

4.40 ± 1.09

.421

  lnHF (ms2)

3.92 ± 1.23

3.98 ± 1.12

.851

3.98 ± 1.05

3.95 ± 1.25

.926

3.82 ± 1.48

4.00 ± 1.04

.581

3.92 ± 1.23

3.98 ± 1.12

.851

  lnTP (ms2)

4.88 ± 1.05

5.05 ± 0.93

.511

5.06 ± 0.90

4.95 ± 1.05

.630

4.89 ± 1.07

5.04 ± 0.95

.601

4.88 ± 1.05

5.05 ± 0.93

.511

Aripiprazole (n = 48)

 N

17

31

 

17

31

 

9

39

 

17

31

 

  lnLF (ms2)

5.25 ± 0.93

4.30 ± 1.23

.008a

4.53 ± 1.38

4.69 ± 1.13

.665

5.14 ± 1.21

4.52 ± 1.20

.168

5.25 ± 0.93

4.30 ± 1.23

.008a

  lnHF (ms2)

4.61 ± 1.40

3.87 ± 1.47

.097

4.40 ± 1.13

3.99 ± 1.51

.372

4.61 ± 1.51

4.02 ± 1.47

.287

4.61 ± 1.40

3.87 ± 1.47

.097

  lnTP (ms2)

5.79 ± 1.05

4.90 ± 1.25

.017a

5.26 ± 1.35

5.19 ± 1.21

.851

5.69 ± 1.29

5.10 ± 1.23

.211

5.79 ± 1.05

4.90 ± 1.25

.017a

Quetiapine (n = 27)

 N

5

22

 

14

13

 

2

25

 

5

22

 

  lnLF (ms2)

3.85 ± 1.47

3.67 ± 1.30

.790

3.37 ± 1.31

4.07 ± 1.25

.170

4.18 ± 0.97

3.67 ± 1.34

.602

3.85 ± 1.47

3.67 ± 1.30

.790

  lnHF (ms2)

4.60 ± 1.64

3.09 ± 1.57

.237

3.14 ± 1.71

3.41 ± 1.52

.672

5.20 ± 0.27

3.11 ± 1.56

.075

4.60 ± 1.64

3.09 ± 1.57

.237

  lnTP (ms2)

4.70 ± 1.52

4.21 ± 1.38

.486

4.02 ± 1.49

4.61 ± 1.26

.350

5.53 ± 0.46

4.20 ± 1.39

.199

4.70 ± 1.52

4.21 ± 1.38

.486

  1. Data are presented as the mean ± standard deviation
  2. ln natural log-transformed, HF high frequency, LF low frequency, TP total power
  3. aSignificant difference (P < .05; Student’s t-test)
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BMC Psychiatry

ISSN: 1471-244X

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