Effects of ABCB1 gene polymorphisms on autonomic nervous system activity during atypical antipsychotic treatment in schizophrenia

Table 5 Multiple regression analysis results using ANS activity, age, body mass index, PANSS, and type of ABCB1 rs1045642–rs22235048 genotype as independent variables in participants treated with aripiprazole monotherapy

Independent variable	ANS activity
	lnLF		lnHF		lnTP
	Β	P	β	P	β	P
Age (years)	−.043	<.001^a	−.037	.018^a	−.0410	.001^a
BMI (kg/m²)	.042	.145	.026	.534	.0348	.277
PANSS (total score)	−.001	.925	−.014	.253	−.006	.494
Type of rs1045642–rs2235048 genotype (reference category: T/C allele carrier)	.798	.009^a	.618	.148	.745	.024^a

ANS autonomic nervous system, BMI body mass index; ln natural log-transformed, HF high frequency, LF low frequency, PANSS Positive and Negative Syndrome Scale, TP total power
^aSignificant difference (P < .05; multiple regression analysis)

ISSN: 1471-244X