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Table 2 Immunoglobulin in bipolar disorder, schizophtrenia and healthy controls

From: Immunoglobulin sub-class distribution in bipolar disorder and schizophrenia: potential relationship with latent Toxoplasma Gondii infection

Variables

BD (n = 124)

Effet size*

Statistical test, p

p adjusted for age, gender, tobacco and BMI

SZ (n = 75)

Effet size*

Statistical test value, p

p adjusted for age, gender, tobacco and BMI

HC (n = 135)

Effet sizea

Statistical test, p

p adjusted for age, gender, tobacco, BMI and duration of the disease

BD vs C

SZ vs C

BD vs SZ

Number of participants (BD/SZ/HC):

124

   

75

   

135

   

Immunoglobulins (g/l)(mean ± sd)

IgG

10,3 (2,2)

d = 0,72

< 0,0001

0.0016

12,1 (3,4)

 

0.477

 

12,1 (2,5)

d = 0,64

< 0,0001

0.0002

IgG1

5,4 (1,6)

d = 0,60

< 0,0001

0.0076

6,8 (2,2)

 

0.2998

 

6,4 (1,7)

d = 0,74

< 0,0001

< 0,0001

IgG2

3,6 (1,4)

d = 0,43

0.0003

0.407

3,7 (1,3)

d = 0,36

0.0102

0.9952

4,2 (1,4)

 

0.4529

 

IgG3

703,9 (368,4)

 

0.1736

 

706,3 (377,1)

 

0.2209

 

783,1 (468,4)

 

0.9726

 

IgG4

332,3 (310,8)

 

0.1958

 

465,1 (359,6)

 

0.0747

 

388,4 (345,7)

d = 0,40

0.0046

0.161

IgA

2,0 (0,7)

d = 0,25

0.0185

0.111

2,1 (0,9)

 

0.136

 

2,2 (0,9)

 

0.8435

 

IgM

1,0 (0,5)

 

0.2688

 

1,0 (0,5)

 

0.102

 

1,1 (0,6)

 

0.4491

 
  1. aEffect size wad determined using the Cohen’s d coefficient by calculating the mean difference between groups, and then divided by the pooled standard deviation