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Table 4 Characteristics of factors associated with depression in people living with HIV east Africa by their odds ratio, confidence interval strength of association, author and year

From: A systematic review and meta-analysis of epidemiology of depression in people living with HIV in east Africa

Factors

Odds ratio (AOR)

95% Confidence interval

Strength of association

Adjusted for

Author, year

Past history of mania

2.73

1.16–6.40

Moderate, negative

Gender, age, educational status, income, social support, self-efficacy, cognitive impairment, current alcohol use, current alcohol use disorder, duration of ART, CD4 count, WHO clinical staging of HIV disease, tuberculosis

Mpungu, 2011

Mean self efficacy score > 89%

0.61

0.41–0.90

Strong, negative

Gender, age, educational status, income, social support, mania, cognitive impairment, current alcohol use, current alcohol use disorder, duration of ART, CD4 count, WHO clinical staging of HIV disease, tuberculosis

Mpungu, 2011

WHO clinical staging of HIV disease

1.88

1.24–2.44

Moderate, positive

Gender, age, educational status, income, social support, mania, self-efficacy, cognitive impairment, current alcohol use, current alcohol use disorder, duration of ART, CD4 count, mania, tuberculosis

Mpungu, 2011

Tuberculosis

2.37

1.20–4.66

Moderate, positive

Gender, age, educational status, income, social support, mania, self-efficacy, cognitive impairment, current alcohol use, current alcohol use disorder, duration of ART, CD4 count, mania, WHO clinical staging of HIV disease

Mpungu, 2011

Age group 40–49

0.95

0.92–0.98

Strong, negative

AIDS stigma, CD4 counts, sex

Akena, 2012

AIDS stigma

1.65

1.20–1.26

Moderate, positive

Age, CD4 counts, sex

Akena, 2012

CD4 count

0.43

0.20–0.91

Moderate, negative

Age, AIDS stigma, sex

Akena, 2012

Not have enough food security

2.89

1.40–5.98

Moderate, positive

Distance from HIV clinic, When knew HIV status, On ART, social support, negative life events, stress score index

Kinyanda. 2011

Negative life event score 6–10

4.89

1.83–10.06

Strong, positive

Distance from HIV clinic, When knew HIV status, On ART, social support, food security, stress score index

Kinyanda. 2011

Negative life event score 6–11+

16.67

7.01–39.66

Strong, positive

Distance from HIV clinic, When knew HIV status, On ART, social support, food security, stress score index

Kinyanda. 2011

Stress score index> 10

7.18

2.65–19.47

Strong, positive

Distance from HIV clinic, When knew HIV status, On ART, social support, food security, negative life event

Kinyanda. 2011

Food insecurity

3.83

1.58–9.32

Strong, positive

Sex, age educational status, marital status, occupation, residence, number of dependent children, access to food aids, practice of agriculture, ownership of livestock, CD4 level, OIs

Yeneabat, 2017

Presence of OIs

5.20

1.34–20.16

Strong, negative

Sex, age educational status, marital status, occupation, residence, number of dependent children, access to food aids, practice of agriculture, ownership of livestock, CD4 level, food insecurity

Yeneabat, 2017

HIV stage three

2.80

1.50–5.21

Moderate, positive

Age, educational status, marital status, residence, CD4 level, perceived stigma, medication adherence, social support

Tesfaw, 2016

Perceived stigma

3.60

2.23–5.80

Strong, positive

Age, educational status, marital status, residence, CD4 level, HIV stage, medication adherence, socia; support

Tesfaw, 2016

Medication adherence

1.61

1.02–2.55

Moderate, positive

Age, educational status, marital status, residence, CD4 level, HIV stage, social support

Tesfaw, 2016

Social support

2.02

1.25–3.27

Moderate, positive

Age, educational status, marital status, residence, CD4 level, HIV stage, medication adherence

Tesfaw, 2016

Married

0.01

0.01–0.07

Weak, positive

Sexual relationship power scale, age, educational status, heavy drinking, tobacco use, WHO HIV stage, CD4 count, previously treated with ART

Hatcher, 2012

Resilience score

1.28

1.12–1.45

Weak, positive

Study site, age, sex, stigma score, childhood trauma score, negative coping score, negative life event experience

Kinyanda, 2017

Stigma score

1.37

1.08–1.73

Weak, positive

Study site, age, sex, resilience childhood trauma score, negative coping score, negative life event experience

Kinyanda, 2017

Childhood trauma score

1.25

1.02–1.55

Weak, positive

Study site, age, sex, resilience stigma score, negative coping score, negative life event experience

Kinyanda, 2017

Negative scoping score

1.50

1.17–1.92

Moderate, positive

Study site, age, sex, resilience stigma score, childhood trauma, negative life event experience

Kinyanda, 2017

Negative life experience score

1.81

1.46–2.25

Moderate, positive

Study site, age, sex, resilience stigma score, childhood trauma, negative scoring score

Kinyanda, 2017

Male sex

1.633

1.138–2.342

Moderate, positive

Marital status,income, verbal stigma, missed frequency of clinic visit, frequency of clinic visit/month

Mohammed, 2016

Monthly income<500eth.birr

1.924

1.159,3.195

Moderate, positive

Marital status, sex,, verbal stigma, missed frequency of clinic visit, frequency of clinic visit/month

Mohammed, 2016

Had verbal stigma

2.705

1.445,5.063

Moderate, positive

Marital status, sex,, verbal stigma, missed frequency of clinic visit, frequency of clinic visit/month

Mohammed, 2016

Missed frequency of clinic visit past one,two and three weeks

4.35 4.56 and 3.75 respectively

2.20–8.59, 2.42–8.58 and 1.39–9.93 respectively

Strong, positive

Marital status, sex,, verbal stigma, frequency of clinic visit/month

Mohammed, 2016

Once, twice and three times frequency of clinic visit/month

19.033, 13.784 and 22.729

2.095–172.878, 1.430–132.871, and 2.450–210.873 respectively

Strong, positive

Marital status, sex,, verbal stigma, verbal stigma, missed frequency of clinic visit

Mohammed, 2016

Female sex

2.071

1.077–3.985

Moderate, positive

Age, income, HIV stage, hospitalization in past one month, felt stigmatized

Eshetu 2015

Age 30–39

2.761

1.165–6.540

Moderate, positive

Sex, Income, HIV stage, hospitalization in past one month, felt stigmatized

Eshetu 2015

Age 50–59

2.596

1.49–9.94

Moderate, positive

Sex, Income, HIV stage, hospitalization in past one month, felt stigmatized

Eshetu 2015

Age 60–69

19.645

4.02–95.99

Strong, positive

Sex, Income, HIV stage, hospitalization in past one month, felt stigmatized

Eshetu 2015

Income < 200 Birr

3.917

1.559, 9.845

Strong, positive

Age,Sex, HIV stage, hospitalization in past one month, felt stigmatized

Eshetu 2015

Income201–400 Birr

2.796

1.139–6.865

Moderate, positive

Age, Sex, HIV stage, hospitalization in past one month, felt stigmatized

Eshetu 2015

Income 401–700 Birr

2.590

1.058–6.340

Moderate, positive

Age, Sex, HIV stage, hospitalization in past one month, felt stigmatized

Eshetu 2015

HIVStage III

2.317

1.108–4.85

Moderate, positive

Age, Sex, income hospitalization in past one month, felt stigmatized

Eshetu 2015

HIV Stage Iv

8.769

1.93–39.87

Strong, positive

Age, Sex, income hospitalization in past one month, felt stigmatized

Eshetu 2015

Hospitalized in the past one Month

15.26

1.463–159.22

Strong, positive

Age, Sex, income month, felt stigmatized, HIVStage

Eshetu 2015

Felt stigmatized

3.597

1.86–6.95

Strong, positive

Age, Sex, income month,, HIVStage, hospitalized in the past one Month

Eshetu 2015

Age > 50 years

1.93

1.09–3.42

Moderate, positive

Religion, education, marital status, sex, source of income, CD4 level, HIVStage, number of living children

Kaharuza, 2006

Pensions as source of income

1.81

1.24–2.66

Moderate, positive

Religion, education, marital status, sex, CD4 level, HIVStage, number of living children, age

Kaharuza, 2006

Primary education

1.69

1.12–2.52

Moderate, positive

Religion, marital status, sex, CD4 level, HIVStage, number of living children, age, source of income

Kaharuza, 2006

CD4 count 50–99

2.02

1.22–3.36

Moderate, positive

Religion, marital status, sex, education, HIVStage, number of living children, age, source of income

Kaharuza, 2006

CD4 count < 50

2.34

1.39–3.93

Moderate, positive

Religion, education, marital status, sex, HIVStage, number of living children, age, source of income

Kaharuza, 2006

Urban residence

3.19

1.50–6.65

Strong, positive

Sex, marital status, income, educational status, occupation, CD4 level

Berhe, 2013

Income < 200 ETB

4.43

1.35–14.58

Strong, positive

Sex, residence, marital status,, educational status, occupation, CD4 level

Berhe, 2013

Unemployed

2.74

1.34–5.57

Moderate, positive

Sex, residence, marital status, educational status, CD4 level

Berhe, 2013

Government employee

3.56

1.73–7.30

Strong, positive

Sex, residence, marital status, educational status, CD4 level

Berhe, 2013