Fig. 3

Diagram of relationships between SLC6A4 genetic variants, promoter methylation and depression. Solid lines indicate an association. The X denotes the interaction between genetic variants and SLC6A4 methylation in association with depression (dot-dash line). Bolded genetic variants or DNA methylation sites in boxes were independently associated, but also interacted to influence depression risk. Interactions which remained significant following FDR correction are boxed