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Table 2 Potential associations between SLC6A4 DNA methylation and genotype

From: Genotype-dependent associations between serotonin transporter gene (SLC6A4) DNA methylation and late-life depression

CpG unit Genetic variant Average methylation (%) p-valuea
Major homozygote Heterozygote Minor homozygote
3 rs4251417 GG (3.04) GA (2.70) AA (1.56) 0.12
14.15 rs4251417 GG (2.26) GA (1.72) AA (1.67) 0.095
16.17.18.19.20 rs140700 GG (7.14) GA (5.73) AA (4.92) 0.019
  rs6354 AA (7.29) AC (6.43) CC (6.03) 0.054
  rs25531 AA (7.06) AG (5.74) GG (8.44) 0.007
21 rs25528 AA (3.54) AC (4.55) CC (4.94) 0.007
  rs4251417 GG (4.03) GA (3.17) AA (3.06) 0.085
  rs6354 AA (3.53) AC (4.30) CC (4.94) 0.023
  5-HTTLPR LL (3.85) SL (4.03) SS (4.55) 0.077
  1. ap-values calculated by one-way ANOVAs and only those with p < 0.15 shown