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Table 4 Random-effect meta-analyses of tooth loss and dementia risk by subgroup and meta-regression analyses

From: Tooth loss as a risk factor for dementia: systematic review and meta-analysis of 21 observational studies

 

Studies with crude results

Number of estimates

Pooled OR and 95% CI

P-value

% heterogeneity explained

Study design

 

16.52

 Cross-sectional

8

3.76 (2.37–5.98)

< 0.001

 

 Cohort

7

2.10 (1.24–3.24)

< 0.001

 

 Case-control

3

1.76 (1.42–2.18)

0.969

 

Sample size

 

6.90

 >1000

8

3.26 (1.79–5.93)

< 0.001

 

 <1000

10

1.95 (1.51–2.52)

0.008

 

Study region

 

0

 Asia

9

2.73 (1.83–4.07)

< 0.001

 

 Europe

6

2.57 (1.50–4.41)

< 0.001

 

 America

3

2.38 (0.57–9.91)

< 0.001

 

Cognitive assessment

 

0

 MMSE

8

3.12 (1.58–6.18)

< 0.001

 

 Others

10

2.38 (1.73–3.27)

< 0.001

 

 Total

18

2.62 (1.90–3.61)

< 0.001

–

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BMC Psychiatry

ISSN: 1471-244X

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