From: Dementia severity at death: a register-based cohort study
Characteristic | Univariable analysis | Multivariable analysis (n = 452) | |||||
---|---|---|---|---|---|---|---|
Coefficient | 95% CI | P-value | Coefficient | 95% CI | P-value | ||
Age at diagnosis (per 1 year increase) | 0.0 | −0.0 to 0.1 | 0.20 | −0.0 | − 0.1 to 0.1 | 0.75 | |
Sex | Reference category: Male | ||||||
Female | −0.8 | −1.5 to − 0.1 | 0.04 | − 1.4 | −2.8 to − 0.1 | 0.04 | |
Ethnicity | Reference category: White | 0.001* | 0.001* | ||||
Black | −3.4 | −4.8 to − 2.0 | 0.001 | − 3.5 | −5.5 to − 1.5 | 0.001 | |
Asian | − 2.7 | − 4.9 to −0.5 | 0.02 | − 4.7 | −9.0 to − 0.5 | 0.03 | |
Other | −0.3 | −2.6 to 2.0 | 0.80 | −5.2 | −9.7 to − 0.8 | 0.02 | |
Marital status | Reference category: Married | 0.001* | 0.26* | ||||
Widowed | 0.7 | −0.3 to 1.7 | 0.18 | 0.8 | −0.9 to 2.4 | 0.36 | |
Divorced | 1.3 | −0.1 to 2.7 | 0.07 | 2.2 | 0.0 to 4.3 | 0.047 | |
Single | 1.8 | 0.7 to 2.9 | 0.002 | 0.7 | −1.1 to 2.5 | 0.45 | |
Dementia type | Reference category: Alzheimer’s disease | 0.004* | 0.43* | ||||
Vascular dementia | −0.2 | −1.2 to 0.8 | 0.71 | −1.1 | −2.9 to 0.9 | 0.28 | |
Dementia with Lewy bodies | 0.5 | −1.9 to 3.0 | 0.68 | 1.8 | −3.0 to 6.6 | 0.46 | |
Other | 1.8 | 0.5 to 3.0 | 0.008 | 1.0 | −1.0 to 3.0 | 0.33 | |
Unspecified | 1.4 | 0.4 to 2.3 | 0.004 | 0.3 | −1.2 to 1.9 | 0.69 | |
IMD (per 10-unit increase in deprivation) | −0.3 | −0.5 to −0.0 | 0.04 | − 0.4 | −0.8 to − 0.0 | 0.04 | |
HoNOS at diagnosis – problems with**: | Agitation | −2.3 | −3.6 to −1.1 | 0.001 | −2.5 | −4.0 to −1.0 | 0.001 |
Hallucinations | −1.8 | −3.3 to −0.4 | 0.02 | −0.7 | −2.4 to 1.0 | 0.43 | |
Depressed mood | −0.3 | −1.6 to 1.1 | 0.70 | 0.7 | −0.8 to 2.3 | 0.37 | |
Time between diagnosis and death (per 1 year later) | −0.7 | −0.9 to − 0.5 | 0.001 | −0.5 | −1.1 to 0.0 | 0.06 |