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Table 3 Association between clinical and demographic characteristics and mini-mental state examination scores at death

From: Dementia severity at death: a register-based cohort study

Characteristic

 

Univariable analysis

Multivariable analysis (n = 452)

  

Coefficient

95% CI

P-value

Coefficient

95% CI

P-value

Age at diagnosis (per 1 year increase)

0.0

−0.0 to 0.1

0.20

−0.0

− 0.1 to 0.1

0.75

Sex

Reference category: Male

      

Female

−0.8

−1.5 to − 0.1

0.04

− 1.4

−2.8 to − 0.1

0.04

Ethnicity

Reference category: White

  

0.001*

  

0.001*

Black

−3.4

−4.8 to − 2.0

0.001

− 3.5

−5.5 to − 1.5

0.001

Asian

− 2.7

− 4.9 to −0.5

0.02

− 4.7

−9.0 to − 0.5

0.03

Other

−0.3

−2.6 to 2.0

0.80

−5.2

−9.7 to − 0.8

0.02

Marital status

Reference category: Married

  

0.001*

  

0.26*

Widowed

0.7

−0.3 to 1.7

0.18

0.8

−0.9 to 2.4

0.36

Divorced

1.3

−0.1 to 2.7

0.07

2.2

0.0 to 4.3

0.047

Single

1.8

0.7 to 2.9

0.002

0.7

−1.1 to 2.5

0.45

Dementia type

Reference category: Alzheimer’s disease

  

0.004*

  

0.43*

Vascular dementia

−0.2

−1.2 to 0.8

0.71

−1.1

−2.9 to 0.9

0.28

Dementia with Lewy bodies

0.5

−1.9 to 3.0

0.68

1.8

−3.0 to 6.6

0.46

Other

1.8

0.5 to 3.0

0.008

1.0

−1.0 to 3.0

0.33

Unspecified

1.4

0.4 to 2.3

0.004

0.3

−1.2 to 1.9

0.69

IMD (per 10-unit increase in deprivation)

−0.3

−0.5 to −0.0

0.04

− 0.4

−0.8 to − 0.0

0.04

HoNOS at diagnosis – problems with**:

Agitation

−2.3

−3.6 to −1.1

0.001

−2.5

−4.0 to −1.0

0.001

Hallucinations

−1.8

−3.3 to −0.4

0.02

−0.7

−2.4 to 1.0

0.43

Depressed mood

−0.3

−1.6 to 1.1

0.70

0.7

−0.8 to 2.3

0.37

Time between diagnosis and death (per 1 year later)

−0.7

−0.9 to − 0.5

0.001

−0.5

−1.1 to 0.0

0.06

  1. KEY: IMD = Index of Multiple deprivation; HoNOS = Health of the Nation Outcome Scales; clinical symptoms were derived from HoNOS scale
  2. Notes: * overall class effect for categorical variables; ** HoNOS categories dichotomised to 0–1 (no or minor problem) and 2–4 (problem behaviour))