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Table 1 Patient baseline demographics

From: Effectiveness of aripiprazole once-monthly in schizophrenia patients pretreated with oral aripiprazole: a 6-month, real-life non-interventional study

Characteristic

Total (n = 242)

Patients aged ≤35 years (n = 89)

Patients aged > 35 years (n = 153)

P-value

Age, mean (SD), years

43.1 (15.1)

28.8 (4.3)

51.3 (12.7)

< 0.0001a

Sex, male, n (%)

133 (55.0)

57 (64.0)

76 (49.7)

0.0328b

Family status, n (%)

   

<. 0001b

 Single

151 (62.7)

74 (84.1)

77 (50.3)

 

 Married/in a relationship

53 (22.0)

13 (14.8)

40 (26.1)

 

 Divorced

23 (9.5)

1 (1.1)

25 (16.3)

 

 Widowed

11 (4.6)

0 (0.0)

11 (7.2)

 

Employment status, n (%)

   

<. 0001b

 Employed

43 (18.0)

23 (26.4)

20 (13.2)

 

 Unemployed

73 (30.5)

36 (41.4)

37 (24.3)

 

 Annuitant

99 (41.4)

13 (14.9)

86 (56.6)

 

 Housewife/househusband

11 (4.6)

2 (2.3)

9 (5.9)

 

 In school/education/re-education

13 (5.4)

13 (15.0)

0 (0.0)

 

Duration of untreated psychosis, mean (SD), years

1.2 (8.0)

1.4 (3.2)

1.0 (9.8)

0.7719a

Age at diagnosis, mean (SD), years

30.9 (13.0)

23.0 (4.3)

35.3 (14.2)

<. 0001a

Time of diagnosis, n (%)

   

<. 0001b

 Within the last 5 years

78 (32.4)

47 (53.4)

31 (20.3)

 

 More than 5 years ago

163 (67.6)

41 (46.6)

122 (79.7)

 

No. of illness episodes, n (%)

   

0.0002b

 First episode of schizophrenia

19 (7.9)

   

 ≤ 5 episodes

137 (57.1)

64 (72.7)

73 (48.0)

 

 > 5 episodes

103 (42.9)

24 (27.3)

79 (52.0)

 

BMI, mean (SD), kg/m2

29.3 (6.9)

28.6 (7.3)

29.7 (6.6)

0.2381a

 Underweight (<18,5), n (%)

3 (1.3)

3 (3.5)

0 (0.0)

 

 Normal weight (18,5 < 25), n (%)

59 (24.6)

21 (24.1)

38 (24.8)

 

 Overweight (25 < 30), n (%)

95 (39.6)

36 (41.4)

59 (38.6)

 

 Obese (≥ 30), n (%)

83 (34.6)

27 (31.0)

56 (36.6)

 

BPRS at baseline, mean (SD)

54.1 (15.6)c

53.0 (16.1)d

53.7 (15.9)d

0.7608a

CGI-S at baseline, mean (SD)

4.8 (0.8)

4.7 (0.9)

4.8 (0.8)

 

CGI-S at baseline, n (%)

   

0.7081b

 Mildly ill

12 (5.0)

6 (6.8)

6 (4.0)

 

 Moderately ill

79 (32.9)

30 (34.1)

49 (32.2)

 

 Markedly ill

100 (41.7)

33 (37.5)

67 (44.1)

 

 Severely ill

48 (20.0)

19 (21.6)

29 (19.1)

 

 Extremely ill

1 (0.4)

0 (0.0)

1 (0.7)

 
  1. In cases where percentages do not add up to 100, data were missing for some patients
  2. BMI body mass index, BPRS Brief Psychiatric Rating Scale, CGI-S Clinical Global Impressions-Severity Scale, SD standard deviation
  3. at-Test
  4. bFisher’s exact Test
  5. cfull analysis set (last observation carried forward)
  6. dall values