Genetic association of human Corticotropin-Releasing Hormone Receptor 1 (CRHR1) with Internet gaming addiction in Korean male adolescents

Table 2 DRD4 and DAT1 VNTR genotypes and allele frequencies between IGA and non-IGA groups

Gene	Genotype	IGA (n = 116)	Non-IGA (n = 114)	χ²1	p1	Allele type	IGA (n = 116)	Non-IGA (n = 114)	χ²2	p2
Gene		n (%)	n (%)	χ²1			n (%)	n (%)	χ²2
DRD4	l/l	0 (0.0)	0 (0.0)	0.32	.571	l	2 (0.9)	1 (0.4)	0.31	.573
	l/s	2 (1.7)	1 (0.9)			s	230 (99.1)	227 (99.6)
	s/s	114 (98.3)	113 (99.1)
DAT1	7/10	4 (3.4)	5 (4.4)	2.11	.806	7-repeats	4 (7.1)	5 (2.2)	1.05	.787
	9/10	7 (6.0)	4 (3.5)			9-repeats	7 (3.0)	4 (1.8)
	10/10	102 (87.9)	102 (89.4)			10-repeats	218 (94.0)	215 (94.2)
	10/11	3 (2.7)	2 (1.8)			11-repeats	3 (1.3)	4 (1.8)
	11/11	0 (0.0)	1 (0.9)

VNTR variable number of tandem repeats, IGA Internet game addiction, non-IGA non-Internet game addiction; χ²1, χ² in comparison of genotype frequency between IGA and non-IGA; p1, p-value in comparison of genotype frequency between IGA and non-IGA; χ²2, χ² in comparison of allele frequency between IGA and non-IGA; p2, p-value in comparison of allele frequency between IGA and non-IGA; l, 48-base pair repeats ≥5; s, 48-base pair repeats <

ISSN: 1471-244X