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Table 3 Validity for a Case Definition Stratified by Region, Year, Province, and Patient Characteristicsa

From: Validation of a case definition for depression in administrative data against primary chart data as a reference standard

  N Prevalence Admin Data (%) Prevalence Chart Data (%) Sensitivity (%) (95% CI) Specificity (%) (95% CI) PPV (%) (95% CI) NPV (%) (95% CI)
Region
 Rural 990 14.9 18.8 58.6 (51.2, 65.8) 95.2 (93.4, 96.5) 73.7 (65.8, 80.5) 90.9 (88.7, 92.7)
 Urban 2372 15.6 16.9 62.7 (57.8, 67.4) 94.0 (92.9, 95.0) 68.1 (63.1, 72.8) 92.5 (91.3, 93.6)
Year
 2001 1482 16.5 15.9 61.9 (55.3, 69.1) 92.1 (90.4, 93.5) 59.6 (53.2, 65.8) 92.7 (91.1, 94.1)
 2004 1880 14.5 18.7 61.1 (55.8. 66.2) 96.2 (95.1, 97.1) 78.8 (73.4, 83.5) 91.5 (90.0, 92.8)
Province
 AB 1565 14.6 19.2 60.5 (54.7,  66.0) 96.4 (95.2, 97.3) 79.8 (74.0, 84.8) 91.1 (89.4, 92.6)
 BC 1797 16.1 16.0 62.4 (56.5, 68.0) 92.7 (91.2, 93.9) 61.7 (55.9, 67.4) 92.8 (91.4, 94.1)
Sex
 Female 2142 17.6 20.4 61.2 (56.5, 65.8) 93.6 (92.3, 94.7) 70.8 (66.0, 75.4) 90.4 (89.0, 91.8)
 Male 1220 11.6 12.5 61.8 (53.6, 69.6) 95.6 (94.2, 96.8) 66.7 (58.2, 74.4) 94.6 (93.1, 95.9)
Age (years)
 <65 2709 17.0 19.1 61.4 (57.1, 65.6) 93.5 (92.4, 94.5) 69.0 (64.5, 73.2) 91.1 (89.9, 92.3)
  ≥ 65 653 8.7 10.7 61.4 (49.0, 72.8) 97.6 (96.0, 98.7) 75.4 (62.2, 85.9) 95.5 (93.5, 97.0)
Comorbid Presenceb
 Yes 1362 15.1 18.2 58.9 (52.5, 65.1) 94.6 (93.1, 95.9) 70.9 (64.2, 77.0) 91.2 (89.4, 92.8)
 No 2000 15.6 17.0 63.2 (57.9, 68.4) 94.2 (92.9, 95.2) 68.9 (63.5, 74.0) 92.6 (91.2, 93.8)
  1. aStratified analysis used the case definition “2 claims within 1 year or 1 hospital discharge data diagnosis” in 3- year administrative data
  2. bComorbidity includes stroke, dementia, diabetes mellitus, dyslipidemia, coronary artery disease, peripheral vascular disease, congestive heart failure, chronic pulmonary disease, asthma, cancer, hypertension, chronic kidney disease, and dialysis