Amplitude of low-frequency fluctuation (ALFF) may be associated with cognitive impairment in schizophrenia: a correlation study

Table 1 Demographic data of all subjects

	SZ (n = 44)	HC (n = 60)	t/χ²	p
Age (years, mean ± S.D.)	25.00 ± 7.49	30.13 ± 8.49	−3.260	0.250
Sex (female/male)	31/13	37/23	0.352	0.866
Education (years, mean ± S.D.)	14.35 ± 3.73	12.52 ± 3.05	2.659	0.009
Medication (Y/N)	41/3	N/A.
First episode (Y/N)	23/21	N/A.
Duration (month, mean ± S.D.)^a	43.02 ± 42.42	N/A.
Medication-CPZ Equivalent	365.373 ± 150.8	N/A.
BPRS (total, mean ± S.D.)^a	27.25 ± 9.13	18.46 ± 1.57	7.315	< 0.001

Note: SD Standard deviation, Y Yes, N No, N/A None, BPRS Brief Psychiatric Rating Scale
^aincludes missing information for some participants
In the SZ group, 40 were taking atypical antipsychotics including clozapine (y = 0.6903x + 69.747), risperidone (y = 0.0116x + 0.0446), olanzapine (y = 0.0332x + 2.0093), aripiprazole (y = 0.0266x + 5.311), ziprasidone (y = 0.1649x + 46.134) and quetiapine (y = 0.9004x + 85.459) chlorpromazine is represented by “x” in the above formulas, 1 was taking paroxetine, and 3 were not taking any psychotropic medication at the time of scan. All antipsychotic doses were converted to chlorpromazine equivalents using standard procedures, added to demographic data

ISSN: 1471-244X