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Table 2 Case fatality indices– number of suicides involving a given drug per non-fatal self-poisoning episode relative to a. lithium and b. chlorpromazine

From: Relative toxicity of mood stabilisers and antipsychotics: case fatality and fatal toxicity associated with self-poisoning

 

Odds ratio (95% CI)

Single drug only

Single and first listed drug

A. Mood Stabilisers

 Lithium

1.0

1.0

 Sodium Valproate

0.92 (0.35–2.45)

0.66 (0.30–1.49)

 Carbamazepine

2.33 (0.94–5.74)

2.37 (1.16–4.85)

 Lamotrigine

0.68 (0.20–2.28)

0.97 (0.40–2.35)

B. Antipsychotics

 Chlorpromazine

1.0

1.0

 Risperidone

0.06 (0.01–0.47)

0.08 (0.02–0.34)

 Quetiapine

1.12 (0.58–2.18)

1.15 (0.67–1.97)

 Olanzapine

1.84 (0.97–3.52)

1.65 (0.97–2.80)

 Clozapine

18.53 (8.69–39.52)

13.38 (6.88–26.00)