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Table 4 Side effects of first generation antipsychotics and management practices at Amanuel Specialized Mental Hospital

From: Prevalence and management practice of first generation antipsychotics induced side effects among schizophrenic patients at Amanuel Mental Specialized Hospital, central Ethiopia: cross-sectional study

Variable category Frequency(%)
Side effect developed Yes 293 (97.7)
No 7 (2.3)
Management of side effects No side effect management 84 (28.0)
Dose reduction of antipsychotics 51 (17.0)
Trihexyphenidyl given 163 (54.3)
Other interventions 2 (0.7)
Response to side effect management Responded 20 (6.7)
No response 196 (65.3)
Unknown response 84 (28.0)
Side effect managed in accordance with APA guideline Yes 38 (17.6)
No 178 (82.4)
Severity of side effects based on GASS Mild side effects 165 (55.0)
Moderate side effects 127 (42.3)
Severe side effects 8 (2.7)
Type of side effect Cardiovascular 169 (56.3)
Sedation and CNS 149 (49.6)
Extrapyramidal 114 (38.0)
Gastrointestinal 95 (31.7)
Anti-cholinergic 73 (24.3)
Diabetes mellitus 73 (24.3)
Genitourinary 46 (15.3)
Weight gain 61 (20.3)
Hyperprolactinemia 41 (13.7)
  1. APA American Psychiatric Association