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Table 6 Factors associated with the occurrence of first generation antipsychotics related side effects at Amanuel Specialized Mental Hospital

From: Prevalence and management practice of first generation antipsychotics induced side effects among schizophrenic patients at Amanuel Mental Specialized Hospital, central Ethiopia: cross-sectional study

Variable category Side effect developed
Yes No X2 (P)
n (%) n (%)
Age category in years ≤35 144 (49.1) 2 (28.6) 2.1 (0.72)
> 35 149 (51.9) 5 (71.4)
Gender Male 189 (64.5) 6 (85.7) 1.35 (0.24)
Female 104 (35.5) 1 (14.3)
Current substance use Yes 74 (25.3) 0 (0.0) 2.35 (0.13)
No 219 (74.7) 7 (100)
Total daily chlorpromazine equivalent dose of FGAs in mg < 300 165 (56.3) 4 (57.1) 0.45 (0.8)
300–600 111 (37.9) 3 (42.9)
600–1000 17 (5.8) 0 (0.0)
Duration of illness in years < 1 17 (5.8) 0 (0.0) 9.98 (0.04)
1–5 171 (58.4) 6 (85.7)
≥5 105 (35.8) 1 (14.3)
Presence of comorbidity Yes 31 (10.6) 1 (14.3) 0.1 (0.75)
No 262 (89.4) 6 (85.7)
Number of antipsychotics 1 201 (68.6) 6 (85.7) 0.91 (0.34)
≥2 92 (31.4) 1 (14.3)