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Table 6 Factors associated with the occurrence of first generation antipsychotics related side effects at Amanuel Specialized Mental Hospital

From: Prevalence and management practice of first generation antipsychotics induced side effects among schizophrenic patients at Amanuel Mental Specialized Hospital, central Ethiopia: cross-sectional study

Variable category

Side effect developed

Yes

No

X2 (P)

n (%)

n (%)

Age category in years

≤35

144 (49.1)

2 (28.6)

2.1 (0.72)

> 35

149 (51.9)

5 (71.4)

Gender

Male

189 (64.5)

6 (85.7)

1.35 (0.24)

Female

104 (35.5)

1 (14.3)

Current substance use

Yes

74 (25.3)

0 (0.0)

2.35 (0.13)

No

219 (74.7)

7 (100)

Total daily chlorpromazine equivalent dose of FGAs in mg

< 300

165 (56.3)

4 (57.1)

0.45 (0.8)

300–600

111 (37.9)

3 (42.9)

600–1000

17 (5.8)

0 (0.0)

Duration of illness in years

< 1

17 (5.8)

0 (0.0)

9.98 (0.04)

1–5

171 (58.4)

6 (85.7)

≥5

105 (35.8)

1 (14.3)

Presence of comorbidity

Yes

31 (10.6)

1 (14.3)

0.1 (0.75)

No

262 (89.4)

6 (85.7)

Number of antipsychotics

1

201 (68.6)

6 (85.7)

0.91 (0.34)

≥2

92 (31.4)

1 (14.3)