Skip to main content

Table 2 Association between possible predictors (separated for four sets of possible predictors as determined in the methods section), treatment groups (EMC/TAU) and remission at endpoint

From: Predictors of the effectiveness of an early medication change strategy in patients with major depressive disorder

Possible predictor Criteria Odds ratio (Expo [β]) p-value Bonferroni holm corrected p-value1
Age treatment group 0.398 0.413 0.007
subtype 0.360 0.431 0.008
subtype*group 1.013 0.673 0.017
Sex treatment group 0.398 0.457 0.010
subtype 0.760 0.807 0.050
subtype*group 1.303 0.724 0.025
Age of onset treatment group 0.228 0.159 0.005
subtype 0.952 0.329 0.006
subtype*group 1.033 0.318 0.006
Prior medication treatment group 1.481 0.484 0.013
subtype 7.600 0.087 0.005
subtype*group 0.183 0.031 0.004
Course of depression (1. episode/recurrent MDD) treatment group 0.325 0.029 0.017
subtype 0.229 0.229 0.050
subtype*group 0.061 0.041 0.025
Melancholic MDD treatment group 0.962 0.956 0.050
subtype 1.337 0.820 0.013
subtype*group 0.539 0.460 0.006
Anxious depression treatment group 0.700 0.532 0.007
subtype 0.795 0.839 0.017
subtype*group 0.785 0.748 0.010
Atypical MDD treatment group 0.275 0.019 0.004
subtype 0.174 0.174 0.005
subtype*group 5.339 0.032 0.005
MDD with Suicidality treatment group 0.933 0.922 0.025
subtype 1.620 0.713 0.008
subtype*group 0.518 0.430 0.006
Comorbid axis I disorder treatment group 0.491 0.202 0.008
subtype 0.712 0.761 0.025
subtype*group 0.617 0.617 0.017
Comorbid axis II disorder treatment group 0.561 0.195 0.007
subtype 0.489 0.551 0.013
subtype*group 1.084 0.921 0.050
CIRS sum score treatment group 1.601 0.506 0.010
subtype 1.352 0.175 0.006
subtype*group 0.778 0.119 0.006
  1. 1 in B-H correction, results are defined as significant (bold) if the p-value of the regression analysis is lower or equal as the B-H corrected p-value; * logistic regression analyses; MDD Major depressive disorder, CIRS Cumulative Illness Rating Scale