Prevalence, correlates for early neurological disorders and association with functioning among children and adolescents with HIV/AIDS in Uganda

Table 3 Association between neurological disorders and adverse outcomes

Outcomes	Enuresis/ Encopresis aOR, p-value^a	Motor/ Vocal TICS aOR, p-value^a	Epilepsy aOR, p-value^a	Any neurological disorder aOR, p-value^a
Any poor social functioning (Suffered disciplinary measures ie suspension, dismissal)^f	0.73 (0.16, 3.27)	0.71 (0.23, 2.15)	1.10 (0.43, 2.77)	1.06 (0.31, 3.61)
	*P = 0.7*	*P = 0.5*	*P = 0.8*	*P = 0.9*
Any days missed at school in the last term^f	0.89 (0.59, 1.35)	0.93 (0.67, 1.30)	1.35 (0.99, 1.85)	1.17 (0.78, 1.74)
Any days missed at school in the last term^f	*P = 0.6*	*P = 0.7*	*P = 0.06*	*P = 0.4*
Any visit to the health unit in the last month^c,f	O.44 (0.17, 1.13)	0.57 (0.30, 1.06)	0.98 (0.59, 1.63)	1.39 (0.76, 2.56)
Any visit to the health unit in the last month^c,f	*P = 0.09*	*P = 0.08*	*P = 0.9*	*P = 0.3*
Any admission to hospital in last 6 months^c,6	0.66 (0.15, 2.91)	0.94(0.34, 2.60)	0.85 (0.34, 2.13)	1.29 (0.44, 3.79)
Any admission to hospital in last 6 months^c,6	*P = 0.6*	*P = 0.9*	*P = 0.7*	*P = 0.6*
Early onset of sexual intercourse^b,e,f	N/A	0.78 (0.26, 2.30)	1.87 (0.56, 6.21)	4.06 (1.26, 13.1)
Early onset of sexual intercourse^b,e,f	N/A	*P = 0.7*	*P = 0.3*	*P = 0.02*
Any non-adherence to ART in last 3 days^b,d,f	N/A	0.78 (0.33, 1.85)	1.21 (0.46, 3.21)	1.60 (0.55, 4.66)
Any non-adherence to ART in last 3 days^b,d,f	N/A	*P = 0.6*	*P = 0.7*	*P = 0.4*

^aAdjusted for age, sex, study site and ethnicity
^bonly asked in adolescents,
^cAdjusted for CD4 cell count at baseline
^dNon adherence to ART adjusted for CD4 count at baseline and whether CA-HIV on ART
N/A – outcome does not vary
^eBonferroni adjusted p value is 0.02*3 = 0.06
^fBonferroni adjusted p value is > 0.1

ISSN: 1471-244X