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Table 1 Therapeutic strategies depending on comorbid anxiety disorder

From: Clinical guidelines for the management of depression with specific comorbid psychiatric conditions French recommendations from experts (the French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental)

Comorbidity

First intention

Second intention

Contra-indications

Obsessive-compulsive disorders

- SSRI

- SNRI

- Psychotherapy in combination

- Imipraminic

- α2 Antagonist

- Association of two ATDs from different pharmacological class

- Potentiation with AAP

- Tianeptine

- Irreversible non selective MAOI

- First-generation antipsychotic

- Anticonvulsant

- Bupropion

Panic disorders

- Imipraminic

- α2 Antagonist

- Association of ATDs

- Anticonvulsant

- First-generation antipsychotic

- AAP

Social anxiety

Generalised anxiety disorder

Post-traumatic stress disorder

  1. AAP Atypical antipsychotic, ATD Antidepressant, MAOI monoamine oxidase inhibitor, SSRI Selective serotonin reuptake inhibitors; SNRI: Dual serotonin and norepinephrine reuptake inhibitors