| Intervention group (n = 285) | Control group (n = 285) | ||
---|---|---|---|---|
Characteristics | n/total valid n | % | n/total valid n | % |
Demographics | ||||
 Age, mean ± SD (total valid n), y | 59.1 ± 9.8 (285) |  | 59.3 ± 9.3 (285) |  |
 Female sex | 61/285 | (21.4) | 59/285 | (20.7) |
 Married | 170/268 | (63.4) | 185/271 | (68.3) |
Socioeconomic status | ||||
 Low | 117/285 | (45.0) | 123/261 | (47.1) |
 Medium | 84/285 | (32.3) | 71/261 | (27.2) |
 High | 59/285 | (22.7) | 67/261 | (25.7) |
Baseline medical data | ||||
 Hypertension | 252/281 | (89.7) | 245/280 | (87.5) |
 Hyperlipidemia | 236/273 | (86.4) | 240/270 | (88.9) |
 Diabetes mellitus | 69/275 | (25.1) | 70/279 | (25.1) |
 TSH, mean ± SD (total valid n), mU/l | 1.6 ± 1.1 (187) |  | 1.5 ± 1.2 (175) |  |
 BMI, mean ± SD (total valid n), kg/m2 | 28.5 ± 5.0 (280) |  | 28.4 ± 4.8 (275) |  |
 Smokers | 90/282 | (31.9) | 97/284 | (34.2) |
 Physically active | 140/285 | (49.1) | 120/285 | (42.1) |
 Previous myocardial infarction | 139/271 | (51.3) | 161/273 | (59.0) |
 Previous CABG | 53/283 | (18.7) | 45/282 | (16.0) |
 Recent acute myocardial infarction | 93/285 | (32.6) | 94/285 | (33.0) |
 Recent coronary intervention (PCI, CABG) | 204/285 | (71.6) | 206/285 | (72.3) |
 NYHA class I-II | 240/285 | (84.2) | 242/285 | (84.9) |
 NYHA class III | 45/285 | (15.8) | 43/285 | (15.1) |
 Charlson Comorbidity Index, median (IQR) | 2 | (1/3) | 2 | (1/3) |
 SF-36, mean ± SD (total valid n), | 59.0 ± 24.9 (268) |  | 55.6 ± 26.4 (271) |  |
Baseline medication | ||||
 Thyroid substitution | 34/285 | (11.9) | 30/285 | (10.5) |
 Continued intake (until T3) | 11/285 | (3.9) | 14/285 | (4.9) |
 Uric acid lowering agents | 24/285 | (8.4) | 24/285 | (8.4) |
 Antibiotics | 2/285 | (0.7) | 2/285 | (0.7) |
 ACE inhibitors | 187/285 | (65.6) | 193/285 | (67.7) |
 Aspirin | 257/285 | (90.2) | 262/285 | (91.9) |
 β-Blockers | 246/285 | (86.3) | 257/285 | (90.2) |
 Statins | 256/285 | (89.8) | 265/285 | (93.0) |
 Antidepressant medication | 33/285 | (11.6) | 36/285 | (12.6) |
HADS-D depression subscale, mean ± SD (total valid n) | ||||
 Baseline | 10.4 ± 2.5 (284) |  | 10.4 ± 2.5 (284) |  |
 After 18 months (T3) | 8.7 ± 4.1 (284) |  | 8.9 ± 3.9 (285) |  |