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Fig. 3 | BMC Psychiatry

Fig. 3

From: Variation in the CACNB2 gene is associated with functional connectivity of the Hippocampus in bipolar disorder

Fig. 3

a Main effect of genotype showing that carriers of high-risk A-allele exhibited higher rs-FC than carriers of C- between the hippocampus and the regions of right inferior temporal, fusiform, and left inferior occipital gyri (independent t-test, p <0 .001). b Interaction graph showing that in BD patients rs-FC was decreased between the hippocampus and right pars triangularis in A-allele carrying individuals compared to that of C-allele carrying individuals, in HC the AA/CA group showed higher rs-FC than CC group, and in carrying C-allele groups the patients with BD had significantly increased rs-FC compared to that of HC

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