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Table 3 Associations of depression and anxiety with NYHA classes using binary and ordinal logistic regression models

From: Associations of mood symptoms with NYHA functional classes in angina pectoris patients: a cross-sectional study

  NYHA classes Gender Age Education  
NYHA class II vs I NYHA class III /IV vs I overall female vs male per 1 year increase 7-9 vs less than 6 years 10-12 vs less than 6 years more then 12 vs less than 6 years overall
Odds Ratio (95% CI) p value Odds Ratio (95% CI) p value p value Odds Ratio (95% CI) p value Odds Ratio (95% CI) p value Odds Ratio (95% CI) p value Odds Ratio (95% CI) p value Odds Ratio (95% CI) p value p value
Stable angina pectoris
 depression as dichotomous variable 0.98 (0.28,3.47) 0.98 5.01 (1.30,19.3) .019 .010 1.48 (0.47,4.67) 0.51 0.98 (0.93,1.04) 0.56 0.51(0.12,2.15) 0.36 1.25(0.31,5.07) 0.75 0.93(0.23,3.83) 0.92 0.64
 as ordinal variable 0.84 (0.41,1.71) 0.63 4.36 (1.77,10.7) .001 <.001 2.27 (1.11,4.66) 0.030 1.00 (0.97,1.04) 0.97 0.62(0.26,1.49) 0.29 1.30(0.52,3.24) 0.58 0.98(0.40,2.38) 0.97 0.41
Unstable angina pectoris
 depression as dichotomous variable 1.52 (0.52,4.47) 0.44 2.49 (0.60,10.4) 0.21 0.46 0.87 (0.33,2.27) 0.78 0.99 (0.94,1.04) 0.60 0.30(0.10,0.88) .029 0.19(0.05,0.75) .017 0.27(0.08,0.93) .038 .026
 as ordinal variable 1.61 (0.84,3.10) 0.15 4.39 (1.77,10.9) .001 .005 1.48 (0.80.2.74) 0.21 0.99 (0.97,1.02) 0.68 0.32(0.16,0.64) .001 0.26(0.12,0.56) <.001 0.25(0.11,0.55) <.001 <.001
Angina pectoris
 depression as dichotomous variable 1.32 (0.59,2.96) 0.50 3.32 (1.28,8.61) .013 .021 1.06 (0.52,2.19) 0.87 0.99 (0.95,1.02) 0.45 0.38(0.16,0.87) .023 0.43(0.18,1.06) .065 0.43(0.18,1.04) .060 .074
 as ordinal variable 1.17 (0.73,1.88) 0.52 3.94 (2.11,7.36) <.001 <.001 1.73 (1.09,2.75) .019 1.00 (0.98,1.02) 0.83 0.43(0.25,0.72) .002 0.50(0.28,0.88) .016 0.44(0.25,0.79) .005 .006
Stable angina pectoris
 anxiety as dichotomous variable 2.59 (0.29,22.9) 0.39 3.59 (0.30,43.4) 0.32 0.59 1.21 (0.23,6.41) 0.82 0.98 (0.90,1.06) 0.56 #
 as ordinal variable 1.13 (0.52,2.44) 0.76 0.80 (0.28,2.33) 0.69 0.77 1.71 (0.82,3.59) 0.16 1.00 (0.96,1.04) >0.99 #
Unstable angina pectoris
 anxiety as dichotomous variable 0.85 (0.24,3.01) 0.80 2.27 (0.47,10.9) 0.31 0.36 1.08 (0.29,3.97) 0.91 0.98 (0.93,1.04) 0.55 0.82(0.22,3.07) 0.76 0.39(0.07,2.22) 0.29 0.62(0.13,2.89) 0.54 0.74
 as ordinal variable 0.98 (0.51,1.88) 0.94 1.37 (0.51,3.66) 0.53 0.74 2.27 (1.19,4.33) .013 0.96 (0.93,0.99) .014 0.50(0.25,1.02) .058 0.45(0.20,0.99) .047 0.17(0.06,0.46) <.001 .005
Angina pectoris
 anxiety as dichotomous variable 1.21 (0.41,3.53) 0.73 2.39 (0.66,8.73) 0.19 0.35 0.93 (0.33,2.63) 0.88 0.97 (0.93,1.02) 0.28 0.37(0.12,1.20) 0.10 0.38(0.11,1.35) 0.13 0.46(0.14,1.53) 0.21 0.29
 as ordinal variable 0.99 (0.60,1.92) 0.97 0.96 (0.47,1.95) 0.91 0.99 1.93 (1.18,3.16) .008 0.98 (0.95,1.00) .050 0.50(0.29,0.88) .017 0.56(0.30,1.03) .063 0.36(0.19,0.69) .002 .013
  1. Abbreviation: NYHA class New York Heart Association functional class, BMI body mass index
  2. #: due to the limitation of small sample size, binary and ordinal logistic regression models were only adjusted for age, sex, and BMI for patients with stable angina pectoris