Selective micro-structural integrity impairment of the isthmus subregion of the corpus callosum in alcohol-dependent males

Table 2 The diffusion metrics of corpus callosum subregions

Region	FA		AD		RD		MD
	PT	HC	PT	HC	PT	HC	PT	HC
Subregion 1	0.47 ± 0.05	0.48 ± 0.03	1.41 ± 0.09	1.36 ± 0.09	0.64 ± 0.10	0.60 ± 0.06	0.91 ± 0.09	0.85 ± 0.06 ^*
Subregion 2	0.54 ± 0.04	0.55 ± 0.02	1.40 ± 0.04	1.37 ± 0.04 ^*	0.55 ± 0.06	0.52 ± 0.04	0.83 ± 0.05	0.80 ± 0.04 ^*
Subregion 3	0.49 ± 0.04	0.50 ± 0.03	1.39 ± 0.04	1.35 ± 0.05 ^*	0.60 ± 0.06	0.58 ± 0.05	0.87 ± 0.05	0.83 ± 0.05
Subregion 4	0.50 ± 0.04	0.50 ± 0.03	1.44 ± 0.04	1.41 ± 0.04 ^*	0.62 ± 0.06	0.59 ± 0.05	0.89 ± 0.05	0.87 ± 0.04
Subregion 5	0.49 ± 0.03	0.51 ± 0.03	1.47 ± 0.04	1.43 ± 0.05 ^*	0.64 ± 0.06	0.60 ± 0.06 ^*	0.92 ± 0.05	0.88 ± 0.05 ^*
Subregion 6	0.46 ± 0.03	0.49 ± 0.03 ^*	1.53 ± 0.08	1.47 ± 0.05 ^**	0.71 ± 0.08	0.64 ± 0.06 ^**	0.98 ± 0.08	0.92 ± 0.05 ^**
Subregion 7	0.55 ± 0.02	0.56 ± 0.02	1.57 ± 0.04	1.55 ± 0.05	0.59 ± 0.04	0.57 ± 0.04	0.92 ± 0.03	0.90 ± 0.04
Whole CC	0.53 ± 0.02	0.54 ± 0.02	1.50 ± 0.03	1.47 ± 0.04 ^*	0.60 ± 0.04	0.57 ± 0.03 ^*	0.90 ± 0.04	0.87 ± 0.03 ^*

** P < 0.01, * 0.01 < P < 0.05
For illustration, all values of AD, RD and MD were multiplied by 1000
Abbreviations: CC corpus callosum, FA Fractional Anisotropy, AD axial diffusivity; RD radial diffusivity, MD Mean diffusivity, HC healthy controls, PT alcohol-dependent patients
Entries in boldface are diffusion metrics with significant inter-group differences (P < 0.05)

ISSN: 1471-244X