Table 2 ACC Metabolite Levels and Tissue Composition in the OCD and HC groups

MRS metabolite

Mean ± SD (iu⁺)

Mean ± SD (iu)

t(df)

p

 GABA+

2.41 ± 0.59

2.10 ± 0.35

2.05 (41)

0.047*

 Glx

2.10 ± 0.49

2.23 ± 0.38

−0.97 (41)

0.34

 GABA+/Glx Ratio

1.18 ± 0.30

0.96 ± 0.22

2.70 (41)

0.01*

Tissue composition

Mean Percentage ± SD

Mean ± SD

t(df)

p

 Cerebral spinal fluid

0.17 ± 0.02

0.16 ± 0.02

1.82 (41)

0.0781

 Gray matter

0.52 ± 0.03

0.52 ± 0.03

/

0.752

 White matter

0.31 ± 0.04

0.32 ± 0.03

1.59 (41)

0.3431