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Table 3 MRS measures as a function of patient subgroups

From: Investigation of anterior cingulate cortex gamma-aminobutyric acid and glutamate-glutamine levels in obsessive-compulsive disorder using magnetic resonance spectroscopy

MRS metabolite

un-medicated OCD (n = 5)

refractory OCD (n = 18)

t(df)

p

severe OCD (n = 16)

moderate OCD (n = 7)

t(df)

p

GABA+

2.43 ± 0.23

2.40 ± 0.66

0.093 (21)

0.927

2.37 ± 0.61

2.48 ± 0.58

0.404 (21)

0.69

Glx

1.93 ± 0.42

2.15 ± 0.51

0.903 (21)

0.377

2.12 ± 0.56

2.06 ± 0.32

0.258 (21)

0.80

GABA+/Glx Ratio

1.31 ± 0.34

1.15 ± 0.29

1.116 (21)

0.277

1.16 ± 0.30

1.22 ± 0.32

0.436 (21)

0.667

  1. ACC anterior cingulate cortex, GABA gamma-aminobutyric acid, Glx glutamate-glutamine, HC healthy control, MRS magnetic resonance spectroscopy, OCD obsessive-compulsive disorder
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BMC Psychiatry

ISSN: 1471-244X

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