Skip to main content

Table 3 MRS measures as a function of patient subgroups

From: Investigation of anterior cingulate cortex gamma-aminobutyric acid and glutamate-glutamine levels in obsessive-compulsive disorder using magnetic resonance spectroscopy

MRS metabolite un-medicated OCD (n = 5) refractory OCD (n = 18) t(df) p severe OCD (n = 16) moderate OCD (n = 7) t(df) p
GABA+ 2.43 ± 0.23 2.40 ± 0.66 0.093 (21) 0.927 2.37 ± 0.61 2.48 ± 0.58 0.404 (21) 0.69
Glx 1.93 ± 0.42 2.15 ± 0.51 0.903 (21) 0.377 2.12 ± 0.56 2.06 ± 0.32 0.258 (21) 0.80
GABA+/Glx Ratio 1.31 ± 0.34 1.15 ± 0.29 1.116 (21) 0.277 1.16 ± 0.30 1.22 ± 0.32 0.436 (21) 0.667
  1. ACC anterior cingulate cortex, GABA gamma-aminobutyric acid, Glx glutamate-glutamine, HC healthy control, MRS magnetic resonance spectroscopy, OCD obsessive-compulsive disorder