Table 1 Socio-demographic characteristics of acne vulgaris patients and healthy controls
|  | Acne vulgaris patients (n = 118) | Healthy controls (n = 59) | P-value a |
|---|---|---|---|
Demographic variables (n (%)) | |||
 Age (yrs.) | 20.97 ± 1.54 | 21.02 ± 1.50 | 0.746 |
 Gander (f/m) | 68/50 | 23/36 | 0.312 |
 Drop out and unemployed | 21 (18) | 13 (22) | 0.50 |
 High family annual income | 69 (58) | 42 (71) | 0.099 |
 Family history of acne vulgaris | 26 (22) | 11 (19) | 0.601 |
 Disease durations (yrs.) | 4.86 ± 2.44 | – | – |
Medication variables (%) | |||
 Oral isotretinoin | 42.37 | – | – |
 Oral antibiotics | 38.14 | – | – |
Quality of life variables | |||
 PHQ-9 | 6.17 ± 4.55 | 3.44 ± 2.17 | < 0.001 |
 AIS | 5.66 ± 3.49 | 4.03 ± 1.90 | 0.002 |
 GAGS | 20.19 ± 6.92 | – | – |
 DLQI | 5.83 ± 4.69 | – | – |
Laboratory variables | |||
 BDNF (ng/ml) | 13.35 ± 2.65 | 14.35 ± 2.70 | 0.038 |
 IL-6 (pg/ml) | 36.43 ± 10.14 | 36.40 ± 11.55 | 0.681 |
 TNF- α (pg/ml) | 455.28 ± 224.13 | 418.82 ± 201.14 | 0.256 |