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Table 1 Socio-demographic characteristics of acne vulgaris patients and healthy controls

From: Association of brain-derived neurotrophic factor levels and depressive symptoms in young adults with acne vulgaris

  Acne vulgaris patients (n = 118) Healthy controls (n = 59) P-value a
Demographic variables (n (%))
 Age (yrs.) 20.97 ± 1.54 21.02 ± 1.50 0.746
 Gander (f/m) 68/50 23/36 0.312
 Drop out and unemployed 21 (18) 13 (22) 0.50
 High family annual income 69 (58) 42 (71) 0.099
 Family history of acne vulgaris 26 (22) 11 (19) 0.601
 Disease durations (yrs.) 4.86 ± 2.44
Medication variables (%)
 Oral isotretinoin 42.37
 Oral antibiotics 38.14
Quality of life variables
 PHQ-9 6.17 ± 4.55 3.44 ± 2.17 < 0.001
 AIS 5.66 ± 3.49 4.03 ± 1.90 0.002
 GAGS 20.19 ± 6.92
 DLQI 5.83 ± 4.69
Laboratory variables
 BDNF (ng/ml) 13.35 ± 2.65 14.35 ± 2.70 0.038
 IL-6 (pg/ml) 36.43 ± 10.14 36.40 ± 11.55 0.681
 TNF- α (pg/ml) 455.28 ± 224.13 418.82 ± 201.14 0.256
  1. All data expressed as mean ± SD (range) of the mean of individual groups
  2. a Mann-whitney U test and chi-square test were used
  3. Abbreviation: IQR interquartile range, PHQ-9:9-item Patient Health Questionnaire, AIS Athens Insomnia Scale, GAGS Global Acne Grading System, DLQI Dermatology Life Quality Index, BDNF brain-derived neurotrophic factor, IL-6 interleukin-6, TNF-α tumor necrosis factor-alpha, a Mann–Whitney U test and chi-square test were used