Table 2 Characteristics of acne vulgaris patients stratified according the depression
|  | Patients without depression (n = 98) | Patients with depression (n = 20) | P-value a | OR (95%CI) | P-vlaue’ |
|---|---|---|---|---|---|
Demographic variables (n (%)) | |||||
 Age (yrs.) | 20.98 ± 1.57 | 20.95 ± 1.36 | 0.99 | 1.12 (0.66–1.90) | 0.743 |
 Gender (f/m) | 40/48 | 11/9 | 0.149 | 1.33 (0.24–7.45) | 0.743 |
 Graduate with no work (n) | 14 (14) | 7 (35) | 0.027 | 11.05 (1.67–73.12) | 0.013 |
 High family annual income (n) | 64 (65) | 5 (25) | 0.001 | 7.71 (1.69–35.21) | 0.008 |
 Family history of acne vulgaris (n) | 18 (18) | 8 (40) | 0.033 | 0.82 (0.12–5.43) | 0.837 |
 Disease durations (yrs.) | 4 (3–6) | 5.5 (4–7) | 0.267 | 0.96 (0.67–1.38) | 0.839 |
Medication variables | |||||
 Oral isotretinoin | 40.82 | 55 | 0.210 | 0.64 (0.08–4.83) | 0.663 |
 Oral antibiotics | 36.73 | 45 | 0.488 | 1.18 (0.19–7.23) | 0.857 |
Quality of life variables | |||||
 AIS | 4.96 ± 3.06 | 9.10 ± 3.39 | 0.000 | 1.52 (1.17–1.98) | 0.002 |
 GAGS | 19.85 ± 6.85 | 21.85 ± 6.98 | 0.297 | 1.01 (0.85–1.19) | 0.920 |
 DLQI | 5.28 ± 4.34 | 8.55 ± 5.32 | 0.01 | 1.06 (0.88–1.28) | 0.558 |
Laboratory findings | |||||
 BDNF (ng/ml) | 13.85 ± 2.47 | 10.96 ± 2.12 | 0.000 | 0.52 (0.35–0.76) | 0.001 |
 IL-6 (pg/ml) | 36.18 ± 10.36 | 37.63 ± 8.89 | 0.247 | 1.02 (0.94–1.11) | 0.671 |
 TNF- α (pg/ml) | 453.40 ± 232.49 | 464.55 ± 177.27 | 0.493 | 1.00 (0.99–1.01) | 0.830 |