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Table 2 Identified differential metabolites between the antenatal depression and non-antenatal depression groups

From: Biomarker screening for antenatal depression in women who underwent caesarean section: a matched observational study with plasma Lipidomics

Metabolites AD vs NAD
ESI+/− FC FDR VIP P-value Bonferroni corrected
SM (d18:1/16:0) + 1.88 < 0.001 5.07 < 0.001 < 0.001
SM (d16:1/18:0) + 2.27 < 0.001 5.42 < 0.001 < 0.001
9Z-Heptatriacontene + 2.03 < 0.001 8.09 < 0.001 < 0.001
PC (16:0/0:0) 2.00 < 0.001 2.20 < 0.001 < 0.001
EB 1213 + 3.30 < 0.001 3.83 < 0.001 < 0.001
3alpha-Hydroxy-7-oxo-5alpha-cholan-24-oic Acid + 2.55 0.001 3.72 0.001 0.035
PC (22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) + 2.65 0.001 1.38 0.002 0.07
cholesterol sulfate 2.49 0.001 1.46 0.003 0.105
PC (18:2(2E,4E)/0:0) + 2.70 0.001 1.12 0.003 0.105
LMST03020057 + 2.48 0.001 3.84 0.004 0.14
PC(16:0/0:0) 2.07 0.001 1.57 0.004 0.14
PC(0:0/18:0) 2.03 0.027 1.58 0.004 0.14
Hexan-1-ol + 3.61 0.001 2.83 0.006 0.21
PE(13:0/22:1(11Z)) + 2.34 0.001 1.16 0.006 0.21
LysoPE (0:0/18:2(9Z,12Z)) + 2.29 0.001 1.01 0.006 0.21
1,25-Dihydroxy-23-oxo-vitamin D3 + 2.04 0.001 1.72 0.007 0.245
SM(d16:1/16:0) 2.36 0.001 1.35 0.007 0.245
Undecylic acid + 2.44 0.001 0.97 0.008 0.28
SM(d18:1/15:0) + 2.18 0.001 1.55 0.009 0.315
5-amino-pentanoic acid + 2.01 0.001 1.03 0.009 0.315
Sorbitan stearate + 4.45 0.001 1.46 0.009 0.315
SM(d16:1/20:1) 2.06 0.001 1.20 0.009 0.315
PC(18:1(9Z)/0:0) + 2.29 0.001 3.48 0.010 0.35
LysoPC (20:3(5Z,8Z,11Z)) + 2.25 0.001 1.56 0.010 0.35
PE(8:0/8:0) + 3.16 0.001 1.83 0.010 0.35
Etretinate 3.34 0.001 1.21 0.011 0.315
13-amino-tridecanoic acid + 3.08 0.001 3.78 0.011 0.315
6-deoxyerythronolide B + 4.77 0.001 2.60 0.013 0.455
PE(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) 2.07 0.002 1.72 0.015 0.525
(7Z,10Z)-hexadecadienoylcarnitine + 3.64 0.002 1.53 0.016 0.56
12-amino-dodecanoic acid + 2.47 0.002 3.66 0.017 0.595
5-((5Z,8Z,11Z,14Z)-heptadeca-5,8,11,14-tetraen-1-yl)resorcinol 4.58 0.002 1.33 0.017 0.595
MG(0:0/18:1(9Z)/0:0) + 2.13 0.002 7.62 0.027 0.945
1-Heptene + 0.47 0.003 3.77 0.034 1.19
8-methoxy-13-hydroxy-9,11-octadecadienoic acid + 2.03 0.003 1.47 0.034 1.19
  1. AD antenatal depression, NAD non-antenatal depression, ESI electrospray ionization, FC fold change, FDR false discovery rate, VIP variable importance in the projection