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Table 2 Identified differential metabolites between the antenatal depression and non-antenatal depression groups

From: Biomarker screening for antenatal depression in women who underwent caesarean section: a matched observational study with plasma Lipidomics

Metabolites

AD vs NAD

ESI+/−

FC

FDR

VIP

P-value

Bonferroni corrected

SM (d18:1/16:0)

+

1.88

< 0.001

5.07

< 0.001

< 0.001

SM (d16:1/18:0)

+

2.27

< 0.001

5.42

< 0.001

< 0.001

9Z-Heptatriacontene

+

2.03

< 0.001

8.09

< 0.001

< 0.001

PC (16:0/0:0)

–

2.00

< 0.001

2.20

< 0.001

< 0.001

EB 1213

+

3.30

< 0.001

3.83

< 0.001

< 0.001

3alpha-Hydroxy-7-oxo-5alpha-cholan-24-oic Acid

+

2.55

0.001

3.72

0.001

0.035

PC (22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)

+

2.65

0.001

1.38

0.002

0.07

cholesterol sulfate

–

2.49

0.001

1.46

0.003

0.105

PC (18:2(2E,4E)/0:0)

+

2.70

0.001

1.12

0.003

0.105

LMST03020057

+

2.48

0.001

3.84

0.004

0.14

PC(16:0/0:0)

–

2.07

0.001

1.57

0.004

0.14

PC(0:0/18:0)

–

2.03

0.027

1.58

0.004

0.14

Hexan-1-ol

+

3.61

0.001

2.83

0.006

0.21

PE(13:0/22:1(11Z))

+

2.34

0.001

1.16

0.006

0.21

LysoPE (0:0/18:2(9Z,12Z))

+

2.29

0.001

1.01

0.006

0.21

1,25-Dihydroxy-23-oxo-vitamin D3

+

2.04

0.001

1.72

0.007

0.245

SM(d16:1/16:0)

–

2.36

0.001

1.35

0.007

0.245

Undecylic acid

+

2.44

0.001

0.97

0.008

0.28

SM(d18:1/15:0)

+

2.18

0.001

1.55

0.009

0.315

5-amino-pentanoic acid

+

2.01

0.001

1.03

0.009

0.315

Sorbitan stearate

+

4.45

0.001

1.46

0.009

0.315

SM(d16:1/20:1)

–

2.06

0.001

1.20

0.009

0.315

PC(18:1(9Z)/0:0)

+

2.29

0.001

3.48

0.010

0.35

LysoPC (20:3(5Z,8Z,11Z))

+

2.25

0.001

1.56

0.010

0.35

PE(8:0/8:0)

+

3.16

0.001

1.83

0.010

0.35

Etretinate

–

3.34

0.001

1.21

0.011

0.315

13-amino-tridecanoic acid

+

3.08

0.001

3.78

0.011

0.315

6-deoxyerythronolide B

+

4.77

0.001

2.60

0.013

0.455

PE(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

–

2.07

0.002

1.72

0.015

0.525

(7Z,10Z)-hexadecadienoylcarnitine

+

3.64

0.002

1.53

0.016

0.56

12-amino-dodecanoic acid

+

2.47

0.002

3.66

0.017

0.595

5-((5Z,8Z,11Z,14Z)-heptadeca-5,8,11,14-tetraen-1-yl)resorcinol

–

4.58

0.002

1.33

0.017

0.595

MG(0:0/18:1(9Z)/0:0)

+

2.13

0.002

7.62

0.027

0.945

1-Heptene

+

0.47

0.003

3.77

0.034

1.19

8-methoxy-13-hydroxy-9,11-octadecadienoic acid

+

2.03

0.003

1.47

0.034

1.19

  1. AD antenatal depression, NAD non-antenatal depression, ESI electrospray ionization, FC fold change, FDR false discovery rate, VIP variable importance in the projection