TY - JOUR AU - Simeone, J. C. AU - Ward, A. J. AU - Rotella, P. AU - Collins, J. AU - Windisch, R. PY - 2015 DA - 2015// TI - An evaluation of variation in published estimates of schizophrenia prevalence from 1990-2013: a systematic literature review JO - BMC Psychiatry VL - 15 UR - https://doi.org/10.1186/s12888-015-0578-7 DO - 10.1186/s12888-015-0578-7 ID - Simeone2015 ER - TY - JOUR AU - Kennedy, J. L. AU - Altar, C. A. AU - Taylor, D. L. AU - Degtiar, I. AU - Hornberger, J. C. PY - 2014 DA - 2014// TI - The social and economic burden of treatment-resistant schizophrenia: a systematic literature review JO - Int Clin Psychopharmacol VL - 29 UR - https://doi.org/10.1097/YIC.0b013e32836508e6 DO - 10.1097/YIC.0b013e32836508e6 ID - Kennedy2014 ER - TY - JOUR AU - Howes, O. PY - 2017 DA - 2017// TI - When the drugs don’t work: the neurobiology of TRS and implications for new therapies JO - Eur Neuropsychopharmacol VL - 27 UR - https://doi.org/10.1016/S0924-977X(17)31966-1 DO - 10.1016/S0924-977X(17)31966-1 ID - Howes2017 ER - TY - JOUR AU - Crilly, J. PY - 2007 DA - 2007// TI - The history of clozapine and its emergence in the US market: a review and analysis JO - Hist Psychiatry VL - 18 UR - https://doi.org/10.1177/0957154X07070335 DO - 10.1177/0957154X07070335 ID - Crilly2007 ER - TY - JOUR AU - Essali, A. AU - Al-Haj Haasan, N. AU - Li, C. AU - Rathbone, J. PY - 2009 DA - 2009// TI - Clozapine versus typical neuroleptic medication for schizophrenia JO - Cochrane Database Syst Rev VL - 21 ID - Essali2009 ER - TY - STD TI - IBM Micromedex DRUGDEX (electronic version). IBM Watson Health, Greenwood Village, Colorado, USA. Available at https://www.micromedexsolutions.com. ). UR - https://www.micromedexsolutions.com ID - ref6 ER - TY - JOUR AU - Honigfeld, G. AU - Arellano, F. AU - Sethi, J. AU - Bianchini, A. AU - Schein, J. PY - 1998 DA - 1998// TI - Reducing clozapine-related morbidity and mortality: 5 years of experience with Clozaril National Registry JO - J Clin Psychiatry VL - 59 ID - Honigfeld1998 ER - TY - STD TI - Smith RL, Haslemo T, Andreassen OA, Eliasson E, Dahl ML, Spigset O, Molden E. Correlation between serum concentrations of N-Desmethylclozapine and granulocyte levels in patients with schizophrenia: a retrospective observational study. CNS Drugs. 2017;57–64. ID - ref8 ER - TY - JOUR AU - Berk, M. AU - Copolov, D. AU - Dean, O. AU - Lu, D. AU - Jeavons, S. AU - Schapkaitz, I. AU - Anderson-Hunt, M. AU - Judd, F. AU - Katz, F. AU - Ording-Jespersen, S. AU - Litlle, J. AU - Conus, P. AU - Cuenod, M. AU - Do, K. Q. AU - Bush, A. I. PY - 2008 DA - 2008// TI - N-acetyl cysteine as a glutathione precursor for schizophrenia – a double-blind, randomized, placebo-controlled trial JO - Biol Psychiatry VL - 64 UR - https://doi.org/10.1016/j.biopsych.2008.03.004 DO - 10.1016/j.biopsych.2008.03.004 ID - Berk2008 ER - TY - JOUR AU - Gibson, S. AU - Brand, S. L. AU - Burt, S. AU - Boden, Z. V. R. AU - Benson, O. PY - 2013 DA - 2013// TI - Understanding treatment non-adherence in schizophrenia and bipolar disorder: a survey of what service users do and why JO - BMC Psychiatry VL - 13 UR - https://doi.org/10.1186/1471-244X-13-153 DO - 10.1186/1471-244X-13-153 ID - Gibson2013 ER - TY - JOUR AU - Bachmann, C. J. AU - Aagaard, L. AU - Bernardo, M. AU - Brandt, L. AU - Cartabia, M. AU - Clavenna, A. AU - Fusté, A. C. AU - Furu, K. AU - Garuoliené, D. AU - Hoffmann, F. AU - Hollingworth, S. AU - Huybrechts, K. F. AU - Kalverdijk, L. J. AU - Kawakami, K. AU - Kieler, H. AU - Kinoshita, T. AU - López, S. C. AU - Machado-Alba, J. E. AU - Machado-Duque, M. E. AU - Mahesri, M. AU - Nishtala, P. S. AU - Piovani, D. AU - Reutfors, J. AU - Saastomoinen, L. K. AU - Sato, I. AU - Shuiling-Veninga, C. C. M. AU - Shyu, Y. C. AU - Siskind, D. AU - Skurtveit, S. AU - Verdoux, H. AU - Wang, L. J. AU - Yahni, C. Z. AU - Zoëga, H. AU - Taylor, D. PY - 2017 DA - 2017// TI - Internacional trends in clozpine use: a study in 17 countries JO - Acta Psychiatr Scand VL - 36 UR - https://doi.org/10.1111/acps.12742 DO - 10.1111/acps.12742 ID - Bachmann2017 ER - TY - JOUR AU - Warnez, S. AU - Alessi-Severini, S. PY - 2014 DA - 2014// TI - Clozapine: a review of clinical practice guidelines and prescribing trends JO - BMC Psychiatry VL - 14 UR - https://doi.org/10.1186/1471-244X-14-102 DO - 10.1186/1471-244X-14-102 ID - Warnez2014 ER - TY - JOUR AU - Volpicelli, S. A. AU - Centorrino, F. AU - Puopolo, P. R. AU - Kando, J. AU - Frankenburg, F. R. AU - Baldessarini, R. J. AU - Flood, J. G. PY - 1993 DA - 1993// TI - Determination of clozapine, norclozapine, and clozapine-N-oxide in serum by liquid chromatography JO - Clin Chem VL - 39 ID - Volpicelli1993 ER - TY - STD TI - Guidence for Industry, Bioanalytical method validation, US Department of Health and Human Services, Food and Drug Administration, CDER, CVM, (May 2001). ID - ref14 ER - TY - JOUR AU - Glimer, T. P. AU - Dolder, C. R. AU - Lacro, J. P. AU - Folsom, D. P. AU - Lindamer, L. AU - García, P. AU - Jeste, D. V. PY - 2004 DA - 2004// TI - Adherence to treatment with antipsychotic medication and health care cost among Medicaid beneficiaries with schizophrenia JO - Am J Psychiatry VL - 161 UR - https://doi.org/10.1176/appi.ajp.161.4.692 DO - 10.1176/appi.ajp.161.4.692 ID - Glimer2004 ER - TY - JOUR AU - Leon, J. AU - Dadvand, M. AU - Canuso, C. AU - White, A. O. AU - Stanilla, J. K. AU - Simpson, G. M. PY - 1995 DA - 1995// TI - Schizophrenia and smoking: an epidemiologic survey in a state hospital JO - Am J Psychiatry VL - 152 UR - https://doi.org/10.1176/ajp.152.3.453 DO - 10.1176/ajp.152.3.453 ID - Leon1995 ER - TY - JOUR AU - Buur-Rasmussen, B. AU - Brøsen, K. PY - 1999 DA - 1999// TI - Cytochrome P450 and therapeutic drug monitoring with respect to clozapine JO - Eur Neuropsychopharmacol VL - 9 UR - https://doi.org/10.1016/S0924-977X(99)00033-4 DO - 10.1016/S0924-977X(99)00033-4 ID - Buur-Rasmussen1999 ER - TY - JOUR AU - Spina, A. AU - Avenoso, G. AU - Facciolà, M. G. AU - Scordo, M. G. AU - Ancione, M. AU - Madia, A. G. AU - Ventimiglia, A. AU - Perucca, E. PY - 2000 DA - 2000// TI - Relationship between plasma concentrations of clozapine and norclozapine and therapeutic response in patients with schizophrenia resistant to conventional neuroleptics JO - Psychopharmacology. VL - 148 UR - https://doi.org/10.1007/s002130050028 DO - 10.1007/s002130050028 ID - Spina2000 ER - TY - JOUR AU - Wiciński, M. AU - Weclewicz, M. M. PY - 2018 DA - 2018// TI - Clozapine-induced agranulocytosis/granulocytopenia: mechanisms and monitoring JO - Curr Opin Hematol VL - 25 UR - https://doi.org/10.1097/MOH.0000000000000391 DO - 10.1097/MOH.0000000000000391 ID - Wiciński2018 ER - TY - JOUR AU - Winnie, N. AU - Rossoune, K. AU - Uetrecht, J. PY - 2014 DA - 2014// TI - Effect of clozapine and olanzapine on neutrophil kinetics: implications for drug-induced agranulocytosis JO - Chem Res Toxicol VL - 27 UR - https://doi.org/10.1021/tx500183x DO - 10.1021/tx500183x ID - Winnie2014 ER - TY - JOUR AU - Bergemann, N. AU - Abu-Tair, F. AU - Aderjan, R. AU - Kopitz, J. PY - 2007 DA - 2007// TI - High clozapine concentrations in leukocytes in a patient who developed leukocytopenia JO - Prog Neuro-Psychopharmacol Biol Psychiatry VL - 31 UR - https://doi.org/10.1016/j.pnpbp.2007.03.009 DO - 10.1016/j.pnpbp.2007.03.009 ID - Bergemann2007 ER - TY - JOUR AU - Smith, R. L. AU - Haslemo, T. AU - Andreassen, O. A. AU - Eliasson, E. AU - Dahl, M. L. AU - Spigset, O. AU - Molden, E. PY - 2017 DA - 2017// TI - Correlation between serum concentrations of N-Desmethylclozapine and granulocyte levels in patients with schizophrenia: a retrospective observational study JO - CNS Drugs VL - 31 UR - https://doi.org/10.1007/s40263-017-0469-1 DO - 10.1007/s40263-017-0469-1 ID - Smith2017 ER - TY - JOUR AU - Oyewumi, L. AU - Cernovsky, Z. AU - Freeman, D. AU - Streiner, D. PY - 2002 DA - 2002// TI - Relation of blood counts during clozapine treatment to serum concentrations of clozapine and nor-clozapine JO - Can J Psychiatr VL - 47 UR - https://doi.org/10.1177/070674370204700306 DO - 10.1177/070674370204700306 ID - Oyewumi2002 ER - TY - JOUR AU - Hasegawa, M. AU - Cola, P. AU - Meltzer, H. PY - 1994 DA - 1994// TI - Plasma clozapine and desmethyl clozapine levels in clozapine-induced agranulocytosis JO - Neuropsychopharmacology. VL - 11 UR - https://doi.org/10.1038/npp.1994.34 DO - 10.1038/npp.1994.34 ID - Hasegawa1994 ER - TY - JOUR AU - Maggs, J. AU - Williams, D. AU - Pirmohamed, M. PY - 1995 DA - 1995// TI - The metabolic formation of reactive intermediates from clozapine, a drug associated with agranulocytosis in man JO - J Pharmacol Exp Ther VL - 275 ID - Maggs1995 ER -