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Table 1 Patient demographic and clinical characteristics

From: Patient characteristics, burden and pharmacotherapy of treatment-resistant schizophrenia: results from a survey of 204 US psychiatrists

 TRS
(n = 408)
Non-TRS
(n = 204)
p-value
Age (years), mean (SD)39.3 (11.3)36.0 (11.8)0.001
Distribution, % (n)
  < 180.0 (0)0.5 (1)0.16
 18–246.4 (26)15.2 (31)< 0.001
 25–3432.6 (133)37.7 (77)0.21
 35–4425.2 (103)25.0 (51)0.95
 45–5422.8 (93)10.3 (21)< 0.001
 55–6412.0 (49)10.3 (21)0.53
  ≥ 651.0 (4)1.0 (2)0.50
Male, % (n)73.0 (298)64.7 (132)0.034
Occupational status, % (n)
 Unemployed74.5 (304)45.1 (92)< 0.001
 Employed part-time8.8 (36)23.5 (48)< 0.001
 Employed full-time5.4 (22)11.8 (24)0.005
 In education/studying4.9 (20)9.8 (20)0.021
 Volunteering4.4 (18)7.8 (16)0.081
 Unknown2.0 (8)2.0 (4)0.50
Marital status, % (n)
 Single71.8 (293)68.1 (139)0.35
 Divorced13.5 (55)12.3 (25)0.67
 Married/long-term relationship10.0 (41)15.2 (31)0.063
 Widowed1.2 (5)1.5 (3)0.80
 Unknown3.4 (14)2.9 (6)0.75
Living arrangements, % (n)
 With a partner/family40.9 (167)53.4 (109)0.004
 In a sheltered home29.4 (120)10.8 (22)< 0.001
 Alone20.1 (82)26.0 (53)0.099
 With friends5.4 (22)5.9 (12)0.80
 No fixed address2.9 (12)1.5 (3)0.27
 Unknown1.2 (5)2.5 (5)0.26
Age at symptom onset (years), mean (SD)22.4 (6.0)22.8 (5.9)0.49
Age at diagnosis (years), mean (SD)24.1 (5.8)24.7 (6.5)0.31
Time between symptom onset and diagnosis (years), mean (SD)1.8 (2.3)1.8 (3.0)0.76
Hospitalization status, % (n)
 At least twice (but not currently)72.5 (296)39.7 (81)< 0.001
 Once only (but not currently)13.2 (54)31.4 (64)< 0.001
 Currently hospitalized (also in past)6.4 (26)2.5 (5)0.038
 Currently hospitalized (first time)1.2 (5)0.5 (1)0.39
 Never4.9 (20)23.5 (48)< 0.001
 Unknown1.7 (7)2.5 (5)0.54
Number of hospitalizations (for patients with > 1 hospitalization), mean (SD)(n = 322)(n = 86) 
7.2 (7.0)5.7 (4.2)0.090
Number of suicide attempts, mean (SD)0.9 (1.5)0.5 (1.3)0.004
Distribution, % (n)
 050.0 (204)69.1 (141)< 0.001
 115.4 (63)9.3 (19)0.036
 214.0 (57)3.4 (7)< 0.001
 3 or more8.1 (33)6.4 (13)
 Unknown12.5 (51)11.8 (24)0.79
  1. SD standard deviation; TRS treatment-resistant schizophrenia
  2. p-values in bold are < 0.05