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Table 1 Patient demographic and clinical characteristics

From: Patient characteristics, burden and pharmacotherapy of treatment-resistant schizophrenia: results from a survey of 204 US psychiatrists

  TRS
(n = 408)
Non-TRS
(n = 204)
p-value
Age (years), mean (SD) 39.3 (11.3) 36.0 (11.8) 0.001
Distribution, % (n)
  < 18 0.0 (0) 0.5 (1) 0.16
 18–24 6.4 (26) 15.2 (31) < 0.001
 25–34 32.6 (133) 37.7 (77) 0.21
 35–44 25.2 (103) 25.0 (51) 0.95
 45–54 22.8 (93) 10.3 (21) < 0.001
 55–64 12.0 (49) 10.3 (21) 0.53
  ≥ 65 1.0 (4) 1.0 (2) 0.50
Male, % (n) 73.0 (298) 64.7 (132) 0.034
Occupational status, % (n)
 Unemployed 74.5 (304) 45.1 (92) < 0.001
 Employed part-time 8.8 (36) 23.5 (48) < 0.001
 Employed full-time 5.4 (22) 11.8 (24) 0.005
 In education/studying 4.9 (20) 9.8 (20) 0.021
 Volunteering 4.4 (18) 7.8 (16) 0.081
 Unknown 2.0 (8) 2.0 (4) 0.50
Marital status, % (n)
 Single 71.8 (293) 68.1 (139) 0.35
 Divorced 13.5 (55) 12.3 (25) 0.67
 Married/long-term relationship 10.0 (41) 15.2 (31) 0.063
 Widowed 1.2 (5) 1.5 (3) 0.80
 Unknown 3.4 (14) 2.9 (6) 0.75
Living arrangements, % (n)
 With a partner/family 40.9 (167) 53.4 (109) 0.004
 In a sheltered home 29.4 (120) 10.8 (22) < 0.001
 Alone 20.1 (82) 26.0 (53) 0.099
 With friends 5.4 (22) 5.9 (12) 0.80
 No fixed address 2.9 (12) 1.5 (3) 0.27
 Unknown 1.2 (5) 2.5 (5) 0.26
Age at symptom onset (years), mean (SD) 22.4 (6.0) 22.8 (5.9) 0.49
Age at diagnosis (years), mean (SD) 24.1 (5.8) 24.7 (6.5) 0.31
Time between symptom onset and diagnosis (years), mean (SD) 1.8 (2.3) 1.8 (3.0) 0.76
Hospitalization status, % (n)
 At least twice (but not currently) 72.5 (296) 39.7 (81) < 0.001
 Once only (but not currently) 13.2 (54) 31.4 (64) < 0.001
 Currently hospitalized (also in past) 6.4 (26) 2.5 (5) 0.038
 Currently hospitalized (first time) 1.2 (5) 0.5 (1) 0.39
 Never 4.9 (20) 23.5 (48) < 0.001
 Unknown 1.7 (7) 2.5 (5) 0.54
Number of hospitalizations (for patients with > 1 hospitalization), mean (SD) (n = 322) (n = 86)  
7.2 (7.0) 5.7 (4.2) 0.090
Number of suicide attempts, mean (SD) 0.9 (1.5) 0.5 (1.3) 0.004
Distribution, % (n)
 0 50.0 (204) 69.1 (141) < 0.001
 1 15.4 (63) 9.3 (19) 0.036
 2 14.0 (57) 3.4 (7) < 0.001
 3 or more 8.1 (33) 6.4 (13)
 Unknown 12.5 (51) 11.8 (24) 0.79
  1. SD standard deviation; TRS treatment-resistant schizophrenia
  2. p-values in bold are < 0.05