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Table 2 Prevalence, severity and frequency of current schizophrenia symptoms

From: Patient characteristics, burden and pharmacotherapy of treatment-resistant schizophrenia: results from a survey of 204 US psychiatrists

 TRS
(n = 408)
Non-TRS
(n = 204)
p-value
Positive symptoms
Experiencing any, % (n)84.6 (345)64.2 (131)< 0.001
 Delusions50.7 (207)35.3 (72)< 0.001
 Hallucinatory behavior46.1 (188)24.5 (50)< 0.001
 Conceptual disorganization24.3 (99)17.2 (35)0.046
 Excitement or agitation11.8 (48)9.8 (20)0.47
 Hostility or aggression11.5 (47)4.9 (10)0.008
Severity, mean (SD)a3.0 (1.0)2.5 (1.0)< 0.001
Experienced on a daily basis, % (n)27.5 (95)9.2 (12)< 0.001
Negative symptoms
Experiencing any, % (n)73.3 (299)61.8 (126)0.004
 Blunted affect37.0 (151)30.9 (63)0.14
 Emotional withdrawal35.8 (146)26.5 (54)0.021
 Social withdrawal30.1 (123)21.6 (44)0.025
 Poor rapport16.2 (66)14.2 (29)0.53
Severity, mean (SD)a3.0 (1.0)2.4 (0.9)< 0.001
Experienced on a daily basis, % (n)45.5 (136)20.6 (26)< 0.001
Cognitive symptoms
Experiencing cognitive dysfunction, % (n)37.3 (152)24.0 (49)0.001
Severity, mean (SD)a3.0 (1.0)2.5 (0.9)0.002
Experienced on a daily basis, % (n)61.2 (93)36.7 (18)0.003
  1. aSeverity rated 1 (minimal), 2 (mild), 3 (moderate), 4 (moderate–severe), 5 (severe), or 6 (extreme), for those patients experiencing symptoms
  2. SD standard deviation; TRS treatment-resistant schizophrenia
  3. p-values in bold are < 0.05