Skip to main content

Table 3 Sensitivity analyses of methodological characteristics

From: Prevalence of perinatal depression among HIV-positive women: a systematic review and meta-analysis

Antenatal depression

Postnatal depression

 

Number of studies

Total number of subjects (HIV+/controls)

OR (95% CI)

I2 (%)

P

Number of studies

Total number of subjects (HIV+/controls)

OR (95% CI)

I2 (%)

P

Meta-analysis

 Random-effects model

13

1520/4383

1.42 (1.12, 1.80)

55

 

10

1645/2135

1.58 (1.08, 2.32)

65

 

 Fixed-effects model

13

1520/4383

1.32 (1.15, 1.52)

55

 

10

1645/2135

1.39 (1.13, 1.71)

65

 

Sub group analysis

 Methodological quality

    

0.31

    

0.04

  Low

0

    

0

    

  Medium

6

343/1732

1.88 (0.93, 3.79)

76

 

2

477/259

0.97 (0.64, 1.46)

0

 

  High

7

1177/2651

1.29 (1.11, 1.51)

0

 

8

1168/1876

1.86 (1.16, 2.98)

67

 

Study design

    

0.11

    

0.13

 Cross-sectional

8

808/2428

1.74 (1.19, 2.54)

58

 

7

1119/1763

1.92 (1.11, 3.34)

72

 

 Case-control

2

86/200

1.62 (0.59, 4.45)

73

 

1

49/113

1.55 (0.73, 3.30)

  

 Other

3

626/1755

1.11 (0.91, 1.36)

0

 

2

477/259

0.97 (0.64, 1.46)

0

 

Depression screening tool

    

0.71

    

0.04

 EPDS

7

1095/3714

1.58 (1.13, 2.21)

67

 

4

567/661

2.31 (1.17, 4.56)

69

 

 CES-D

3

225/305

1.25 (0.63, 2.47)

68

 

3

878/679

0.97 (0.72, 1.29)

0

 

 Other

3

200/364

1.30 (0.86, 1.99)

0

 

3

200/795

1.73 (0.82, 3.65)

32

 

Geographical locations

    

0.03

    

0.19

 Africa

11

1331/4165

1.55 (1.20, 2.01)

56

 

8

1457/1917

1.78 (1.12, 2.84)

68

 

 North America

2

189/218

0.88 (0.58, 1.35)

0

 

2

188/218

1.07 (0.58, 1.97)

  
  1. Abbreviations: CES-D Centre for Epidemiologic Surveys for Depression, EPDS Edinburgh Postnatal Depression Scale