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Table 3 Sensitivity analyses of methodological characteristics

From: Prevalence of perinatal depression among HIV-positive women: a systematic review and meta-analysis

Antenatal depression Postnatal depression
  Number of studies Total number of subjects (HIV+/controls) OR (95% CI) I2 (%) P Number of studies Total number of subjects (HIV+/controls) OR (95% CI) I2 (%) P
Meta-analysis
 Random-effects model 13 1520/4383 1.42 (1.12, 1.80) 55   10 1645/2135 1.58 (1.08, 2.32) 65  
 Fixed-effects model 13 1520/4383 1.32 (1.15, 1.52) 55   10 1645/2135 1.39 (1.13, 1.71) 65  
Sub group analysis
 Methodological quality      0.31      0.04
  Low 0      0     
  Medium 6 343/1732 1.88 (0.93, 3.79) 76   2 477/259 0.97 (0.64, 1.46) 0  
  High 7 1177/2651 1.29 (1.11, 1.51) 0   8 1168/1876 1.86 (1.16, 2.98) 67  
Study design      0.11      0.13
 Cross-sectional 8 808/2428 1.74 (1.19, 2.54) 58   7 1119/1763 1.92 (1.11, 3.34) 72  
 Case-control 2 86/200 1.62 (0.59, 4.45) 73   1 49/113 1.55 (0.73, 3.30)   
 Other 3 626/1755 1.11 (0.91, 1.36) 0   2 477/259 0.97 (0.64, 1.46) 0  
Depression screening tool      0.71      0.04
 EPDS 7 1095/3714 1.58 (1.13, 2.21) 67   4 567/661 2.31 (1.17, 4.56) 69  
 CES-D 3 225/305 1.25 (0.63, 2.47) 68   3 878/679 0.97 (0.72, 1.29) 0  
 Other 3 200/364 1.30 (0.86, 1.99) 0   3 200/795 1.73 (0.82, 3.65) 32  
Geographical locations      0.03      0.19
 Africa 11 1331/4165 1.55 (1.20, 2.01) 56   8 1457/1917 1.78 (1.12, 2.84) 68  
 North America 2 189/218 0.88 (0.58, 1.35) 0   2 188/218 1.07 (0.58, 1.97)   
  1. Abbreviations: CES-D Centre for Epidemiologic Surveys for Depression, EPDS Edinburgh Postnatal Depression Scale