Rapid cycling bipolar disorder is associated with antithyroid antibodies, instead of thyroid dysfunction

BMC Psychiatry

Table 2 Comparison of fast serum levels of FT3, FT4, and TSH between RC and NRC

	FT3 (mean ± SD) (pmol/l)	FT4 (mean ± SD) (pmol/l)	TSH (mean ± SD) (μIU/ml)	P^a	P^b	P^c
^dRCBD (n = 47)	4.9 ± 1.7	19.0 ± 15.4	3.2 ± 7.5	0.982^g	0.313^g	0.251^g
Non-RCBD (n = 306)	4.9 ± 0.9	16.7 ± 4.7	1.9 ± 1.6	0.030^h	< 0.001^h	< 0.001^h
^eRCBD (n = 41)	4.7 ± 0.9	19.3 ± 16.0	2.1 ± 1.4	0.982^g	0.313^g	0.251^g
Non-RCBD(n = 292)	4.9 ± 0.9	16.6 ± 4.7	1.9 ± 1.5	0.56^h	< 0.002^h	< 0.792^h
^fRCBD (n = 14)	5.0 ± 0.7	17.0 ± 3.0	1.7 ± 1.0	0.842^g	0.702^g	0.705^g
Non-RCBD (n = 123)	5.1 ± 1.0	17.6 ± 5.7	1.9 ± 1.9	0.894^h	0.592^h	0.485^h

RCBD Rapid cycling bipolar disorder
^aFor FT3
^bFor FT4
^cFor TSH
^dIncluding all the patients
^eExcluding patients with comorbidity of thyroid diseases
^fExcluding patients under pyschopharmaceutical treatment within 3 months prior to recruitment or with comorbidity of thyroid diseases
^gTest for equality of means
^hTest for equality of variance

ISSN: 1471-244X