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Table 1 Prevalence of comorbidities in BPD of the interval 1996–2004 compared to the interval 2008–2012

From: Pharmacotherapy of borderline personality disorder: what has changed over two decades? A retrospective evaluation of clinical practice

 

2008–2012 (N = 86)

1996–2004 (N = 142)

 

% (n)

% (n)

Fisher’s exact (p value)

substance related disorder

55 (47)

79 (112)

0.0002

 alcohol

47 (40)

54 (76)

0.3399

 cannabinoids

24 (21)

27 (38)

0.7563

 sedatives and hypnotics

9 (8)

32 (45)

< 0.0001

 opioids

7 (6)

10 (14)

0.6300

adjustment and somatoform disorders

40 (34)

61 (86)

0.0026

affective disorders

31 (27)

42 (60)

0.1221

adjustment disorders or PTSD

28 (24)

40 (56)

0.0868

anxiety and obsessive-compulsive disorder

21 (18)

20 (29)

1.0000

eating disorder

14 (12)

34 (48)

< 0.0001

behavioral disorder with somatic disturbances

14 (12)

22 (31)

0.1641

emotional dysregulation in childhood

10 (9)

5 (7)

0.1791

personality and behavioral disorder

6 (5)

27 (38)

< 0.0001

  1. Rates in %; N number of patients with documented comorbidities. Bonferroni correction (p < 0.004). Significant p-values are highlighted in bold