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Table 8 Prevalence of psychotropic drugs at time of discharge (1996–2004 versus 2008–2012)

From: Pharmacotherapy of borderline personality disorder: what has changed over two decades? A retrospective evaluation of clinical practice

 Rates of psychotropic drugs1 
2008–20121996–2004
N = 87N = 142Fisher’s exact (p value)
antipsychotics4637.30.2139
antidepressants67.856.30.0953
hypnotics / sedatives24,124,610.000
mood stabilizers9.224.60.0048
valproic acid3.42.8 
carbamazepine3.420.4 
lamotrigine2.30 
naltrexone35.66.3< 0.0001
overall9471.8< 0.0001
 Rates of antipsychotics2 
2008–20121996–2004
N = 40N = 53Fisher’s exact (p value)
low-potency antipsychotics42.583< 0.0001
high-potency antipsychotics5170.1073
second generation antipsychotics6043.30.1438
 Rates of antidepressants3 
2008–20121996–2004
N = 59N = 80Fisher’s exact (p value)
tri−/tetracyclic antidepressants13.653.8< 0.0001
SSRI55.956.30.9702
MAO inhibitors011.3 
atypical antidepressants42.437.50.6013
  1. 1Rates in %; N number of patients of the cohort. Bonferroni correction (p < 0.008). Significant p-values are highlighted in bold
  2. 2Rates in %; reference is number of patients receiving antipsychotics (N). Bonferroni correction (p < 0.016). Significant p-values are highlighted in bold
  3. 3Rates in %; reference is number of patients receiving antidepressants (N). Bonferroni correction (p < 0.0125). Significant p-values are highlighted in bold
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