Table 3 Effect of potential confounders or mediators on the associations between BMI at baseline and episode of mood disorder
From: Association between depression, anxiety and weight change in young adults
Variables | Episode of mood disorder since baseline (vs. those with no history) | PERM | Episode of mood disorder 12 leading to CDAH2 (vs those with no history) | PERM |
|---|---|---|---|---|
Adjusted RR (95% CI) after inclusion of covariate | Adjusted RR (95% CI) after inclusion of covariate | |||
Males | ||||
 Base model | 0.97 (0.90,1.04) |  | 0.94 (0.86,1.03) | – |
  C-reactive protein | 0.94 (0.82,1.08) | −100 | 0.92 (0.84,1.02) | −33.3 |
  Dietary guideline index | 0.95 (0.87,1.03) | −66.7 | 0.94 (0.85,1.03) | 0 |
  Antidepressant use | 0.92 (0.83,1.03) | − 166.7 | 0.94 (0.85,1.04) | 0 |
  Smoking status | 0.94 (0.86,1.03) | 100 | 0.94 (0.85,1.04) | 0 |
  Fibrinogen | 0.91 (0.88,1.06) | 200 | 0.94 (0.85,1.04) | 0 |
  Moderate or vigorous physical activity | 0.88 (0.68,1.12) | 300 | 0.88 (0.72,1.07) | −100 |
  Steps per day | 0.89 (0.69,1.15) | − 266.7 | 0.88 (0.72,1.08) | −100 |
  Extra food consumption | 0.94 (0.83,1.07) | −100 | 0.94 (0.85,1.04) | 0 |
  Smoking status at follow-up | 0.92 (0.81–1.06) | −166.7 | 0.87 (0.72,1.07) | − 116.7 |
  Moderate or vigorous physical activity | 0.88 (0.64,1.20) | 300 | 0.86 (0.70,1.06) | − 133.3 |
  Dietary guideline index | 0.94 (0.80–1.09) | −100 | 0.93 (8.83–1.04) | −16.7 |
  Weight satisfaction | 0.90 (0.76,1.08) | − 233.0 | 0.92 (0.80,1.07) | −33.3 |
  Dietary adherence | 0.86 (0.61,1.21) | − 366.0 | 0.87 (0.70,1.09) | −116.7 |
  Takeaway food consumption | 0.93 (0.78,1.11) | −133.3 | 0.93 (0.83,1.04) | −16.7 |
 Full model | 0.93 (0.78,1.11) | −133.3 | 0.93 (0.83,1.04) | −16.7 |
Females | ||||
 Base model | 1.04 (1.01,1.08) |  | 1.03 (1.00,1.07) | – |
  C-reactive protein | 1.09 (1.01,1.17) | − 125.0 | 1.06 (1.03,1.11) | −100 |
  Dietary guideline index | 1.05 (1.00,1.11) | −25.0 | 1.06 (1.02,1.10) | −100 |
  Antidepressant use | 1.06 (0.99,1.14) | −50.0 | 1.07 (1.02,1.12) | −133.3 |
  Smoking status | 1.07 (1.02,1.13) | −75.0 | 1.06 (1.02,1.10) | −100 |
  Fibrinogen | 1.13 (0.98–1.30) | − 225 | 1.06 (1.01–1.11) | − 100 |
  Moderate or vigorous physical activity | 1.13 (0.98,1.30) | −225 | 1.12 (1.02,1.23) | − 300 |
  Steps per day | 1.15 (0.99,1.33) | 275 | 1.13 (1.00,1.28) | − 333.3 |
  Extra food consumption | 1.07 (1.00,1.15) | −75.0 | 1.06 (1.00,1.13) | −100 |
  Smoking status at follow-up | 1.06 (0.99–1.14) | −50.0 | 1.12 (1.02,1.23) | −300 |
  Moderate or vigorous physical activity at follow-up | 1.06 (0.99,1.14) | −50.0 | 1.06 (1.01,1.11) | −100 |
  Dietary guideline index at follow-up | 1.13 (0.98–1.30) | −225.0 | 1.13 (1.02–1.24) | −333.3 |
  Weight satisfaction | 1.08 (1.00,1.16) | −100 | 1.11 (0.94,1.30) | 266.7 |
  Dietary adherence | 1.15 (0.99,1.33) | − 275.0 | 1.07 (1.00,1.13) | −133.3 |
  Takeaway food consumption | 1.07 (1.00,1.15) | −75.0 | 1.06 (1.00,1.13) | −100 |
 Full model | 1.07 (1.00,1.15) | −75.0 | 1.06 (1.00,1.13) | −100 |