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Table 3 Effect of potential confounders or mediators on the associations between BMI at baseline and episode of mood disorder

From: Association between depression, anxiety and weight change in young adults

VariablesEpisode of mood disorder since baseline (vs. those with no history)PERMEpisode of mood disorder 12 leading to CDAH2 (vs those with no history)PERM
Adjusted RR (95% CI) after inclusion of covariateAdjusted RR (95% CI) after inclusion of covariate
Males
 Base model0.97 (0.90,1.04) 0.94 (0.86,1.03)
  C-reactive protein0.94 (0.82,1.08)−1000.92 (0.84,1.02)−33.3
  Dietary guideline index0.95 (0.87,1.03)−66.70.94 (0.85,1.03)0
  Antidepressant use0.92 (0.83,1.03)− 166.70.94 (0.85,1.04)0
  Smoking status0.94 (0.86,1.03)1000.94 (0.85,1.04)0
  Fibrinogen0.91 (0.88,1.06)2000.94 (0.85,1.04)0
  Moderate or vigorous physical activity0.88 (0.68,1.12)3000.88 (0.72,1.07)−100
  Steps per day0.89 (0.69,1.15)− 266.70.88 (0.72,1.08)−100
  Extra food consumption0.94 (0.83,1.07)−1000.94 (0.85,1.04)0
  Smoking status at follow-up0.92 (0.81–1.06)−166.70.87 (0.72,1.07)− 116.7
  Moderate or vigorous physical activity0.88 (0.64,1.20)3000.86 (0.70,1.06)− 133.3
  Dietary guideline index0.94 (0.80–1.09)−1000.93 (8.83–1.04)−16.7
  Weight satisfaction0.90 (0.76,1.08)− 233.00.92 (0.80,1.07)−33.3
  Dietary adherence0.86 (0.61,1.21)− 366.00.87 (0.70,1.09)−116.7
  Takeaway food consumption0.93 (0.78,1.11)−133.30.93 (0.83,1.04)−16.7
 Full model0.93 (0.78,1.11)−133.30.93 (0.83,1.04)−16.7
Females
 Base model1.04 (1.01,1.08) 1.03 (1.00,1.07)
  C-reactive protein1.09 (1.01,1.17)− 125.01.06 (1.03,1.11)−100
  Dietary guideline index1.05 (1.00,1.11)−25.01.06 (1.02,1.10)−100
  Antidepressant use1.06 (0.99,1.14)−50.01.07 (1.02,1.12)−133.3
  Smoking status1.07 (1.02,1.13)−75.01.06 (1.02,1.10)−100
  Fibrinogen1.13 (0.98–1.30)− 2251.06 (1.01–1.11)− 100
  Moderate or vigorous physical activity1.13 (0.98,1.30)−2251.12 (1.02,1.23)− 300
  Steps per day1.15 (0.99,1.33)2751.13 (1.00,1.28)− 333.3
  Extra food consumption1.07 (1.00,1.15)−75.01.06 (1.00,1.13)−100
  Smoking status at follow-up1.06 (0.99–1.14)−50.01.12 (1.02,1.23)−300
  Moderate or vigorous physical activity at follow-up1.06 (0.99,1.14)−50.01.06 (1.01,1.11)−100
  Dietary guideline index at follow-up1.13 (0.98–1.30)−225.01.13 (1.02–1.24)−333.3
  Weight satisfaction1.08 (1.00,1.16)−1001.11 (0.94,1.30)266.7
  Dietary adherence1.15 (0.99,1.33)− 275.01.07 (1.00,1.13)−133.3
  Takeaway food consumption1.07 (1.00,1.15)−75.01.06 (1.00,1.13)−100
 Full model1.07 (1.00,1.15)−75.01.06 (1.00,1.13)−100
  1. RR relative risk, CI confidence interval, Base model adjusted for: Age, education, duration of follow-up, marital status, self-reported physical health status, history of cardiometabolic diseases, and use of oral contraceptive (in women), PERM percentage of excess risk explained by the mediator